Acitretin

Therapeutic Group

Antipsoriatics

Indication Dosage

Severe Refractory Psoriasis, Palmoplantar pustulosis, Congenitalichthyosis, Darier's Disease: 

  • Adults: Initially 25-30 Mg Daily For 2 To 4 Weeks, Increase Up To 75 Mg Daily, Maintenance; 25-50 Mg Daily. Max Duration Of Treatment 6 Months. 
  • Children: Not Recommended.

Content

  • Cap 10mg /25mg: Acitretin 10mg /25mg.

Pregnancy

Contraindicated

Stability

  • Vitamin a Derivative

Contra Indications

  • Renal Or Hepatic Impairment, Pregnancy; Highly Teratogenic, Exclude Pregnancy Before The Start Of Treatment, Contraceptive Measures Must Be Taken Before, During And For At Least 2 Years After Withdrawal Of Treatment.

Precautions

  • Renal Or Hepatic Impairment, Pregnancy; Highly Teratogenic, Exclude Pregnancy Before The Start Of Treatment, Contraceptive Measures Must Be Taken Before, During And For At Least 2 Years After Withdrawal Of Treatment.

Lactation

  • Contraindicated

Side Effects

  • Severe Headache
  • Dry Skin
  • Sticky Skin
  • Dermatitis
  • Erosion Of Mucosa
  • Erythema
  • Pruritus
  • Palmer And Plantar Exfoliation
  • Rhinitis
  • Epistaxis
  • Nail Fragility
  • Conjunctivitis
  • Xerophthalmia
  • Bullous Eruptions
  • Vulvovaginitis
  • Drowsiness
  • Sweating
  • Gingivitis
  • Alopecia
  • Granulomatous Lesions
  • Gi Upset
  • Decreased Night Vision
  • Hepatotoxicity
  • Change In Serum Lipids
  • Myalgia
  • Arthralgia
  • Hyperostosis And Extraosseous Calcification (long Term Therapy)
  • Photosensitivity
  • Visual Disturbance (withdraw Immediately And Refer For Neurological Examination)

Available Brands