Amantadine

Therapeutic Group

Anti-Parkinson Drugs

Indication Dosage

Amantadine is a medication used to treat Parkinson's disease and to reduce symptoms of influenza (the flu). In simple terms, it helps people with Parkinson's move better and ease the discomfort caused by the flu.

Parkinson's Disease: 

  • Adult: 100 Mg Daily For 1 Week Then Increased To 100 Mg Twice Daily, May Be Administered In Conjunction With Other Treatment. Some Patients May Require Higher Doses; Maximum 400 Mg Per Day 

Post-herpetic Neuralgia: 

  • Adult: 100 Mg Twice Daily For 14 Days (continued For Another 14 Days If Necessary) 

Treatment Of Influenza A (Not Recommended): 

  • Adult: 100 Mg Daily 4-5 Days 

Prophylaxis Of Influenza A (Not Recommended): 

  • Adult: 100 Mg Daily Usually For 6 Weeks Or With Influenza Vaccination For 2-3 Weeks After Vaccination

Content

  • Cap /Tab: Amantadine Sulphate (or Hydrochloride) 100mg.

Pregnancy

Avoid; Risk Of Toxicity

Stability

  • Dopamine Receptor Agonists

Contra Indications

  • Epilepsy, History Of Gastric Ulceration, Severe Renal Disease.

Precautions

  • Epilepsy, History Of Gastric Ulceration, Severe Renal Disease.

Lactation

  • Avoid; Risk of Toxicity

Side Effects

  • Anorexia
  • Anxiety
  • Confusion
  • Dizziness
  • Dry Mouth
  • Gi Disturbances
  • Hallucinations
  • Headache
  • Impaired Concentration
  • Insomnia
  • Lethargy
  • Livedo Reticularis
  • Myalgia
  • Palpitation
  • Peripheral Oedema
  • Postural Hypotension
  • Slurred Speech
  • Sweating
  • Movement Disorders
  • Neuroleptic Malignant Syndrome
  • Psychosis
  • Rash
  • Seizure
  • Tremor
  • Urinary Incontinence
  • Urinary Retention
  • Visual Disturbances.
  • Rare: Heart Failure
  • Leucopenia
  • Photo Sensitisation