Aminophylline

Therapeutic Group

Drugs For Obstructive Airway Diseases, Systemic

Indication Dosage

Severe Acute Asthma: 

By IV Infusion: 

  • Adult & Children Above 12 Yrs: 500-700 Micrograms/kg/hour, Adjusted According To Plasma-theophylline Concentration; (in Patients Not Previously Treated With Theophylline): 250-500 Mg (max. Per Dose 5 Mg/kg) By Slow IV Injection Followed By Intravenous Infusion 
  • Children 1 Month-11 Yrs: 1 Mg/kg/hour, Adjusted According To Plasma-theophylline Concentration; (in Patients Not Previously Treated With Theophylline): 5 Mg/kg (max. Per Dose 500 Mg) By Slow IV Injection Followed By Intravenous Infusion 
  • Elderly: 300 Mcg/kg/hour, Adjusted According To Plasma-theophylline Concentration 

Severe Acute Exacerbation Of Chronic Obstructive Pulmonary Disease: 

By IV Infusion: 

  • Adult: 500-700 Mcg/kg/hour, Adjusted According To Plasma-theophylline Concentration; (in Patients Not Previously Treated With Theophylline): 250-500 Mg (max. Per Dose 5 Mg/kg) By Slow IV Injection Followed By Intravenous Infusion 
  • Elderly: 300 Mcg/kg/hour, Adjusted According To Plasma-theophylline Concentration 

Chronic Asthma: 

Oral: 

  • Children (body weight 40 Kg And Above): Initially 225 Mg Twice Daily For 1 Week, Then Increased If Necessary To 450 Mg Twice Daily, Adjusted According To Plasma Theophylline Concentration 

Reversible Airway Obstruction: 

Oral: 

  • Adult (body weight 40 Kg And Above): Initially 225 Mg Twice Daily For 1 Week, Then Increased If Necessary To 450 Mg Twice Daily, Adjusted According To Plasmatheophylline Concentration

Content

  • Inj: Per ml: Aminophylline 25mg; 10 ml Amp.
  • Tab 100mg: Aminophylline 100mg.
  • Tab 225mg: Aminophylline 225mg; Modified Release Tab .

Pregnancy

Caution Advised

Stability

  • Xanthine

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Caution Advised

Side Effects

  • Cns Stimulation
  • Arrhythmias
  • Convulsions
  • Headache
  • Diarrhoea
  • Gastric Irritation
  • Hypotension
  • Insomnia
  • Nausea
  • Palpitation
  • Tachycardia
  • Vomiting