Calcitriol

Therapeutic Group

Vitamin A, D & Combinations

Indication Dosage

Renal Osteodystrophy: 

  • Adult: Initially 250 Nanograms Daily, Adjusted In Steps Of 250 Nanograms Every 2-4 Weeks If Required; Usual Dose 0.5-1 Microgram Daily 

Renal Osteodystrophy (in Patients With Normal Or Only Slightly Reduced Plasma-calcium Concentration): 

  • Adult: Initially 250 Nanograms Once Daily On Alternate Days, Adjusted In Steps Of 250 Nanograms Every 2-4 Weeks If Required; Usual Dose 0.5-1 Microgram Daily 

Established Postmenopausal Osteoporosis: 

  • Adult: 250 Nanograms Twice Daily, Plasma-calcium Concentration And Creatinine To Be Monitored. 

Hypocalcaemia In Patients Undergoing Dialysis Or Chronic Renal Failure. Reduction Of Parathyroid Hormone In Renal Osteodystrophy: 

By IV Inj: 

  • Adults: Initially: 0.5 Mcg Three Times Weekly 

By IV Inj At The End Dialysis. 

  • Titrate: By 0.25 To 0.5 Mcg At Two To Four Wk Intervals. Maintenance: 0.5-3 Mcg Three Times Weekly. 
  • Children: Not Recommended.

Content

  • Cap 0.25 Mcg /0.5 Mcg: Calcitriol 0.25 Mcg /0.5 Mcg.
  • Inj: 1 Mcg /2 Mcg: Per ml: Calcitriol 1 Mcg /2 Mcg

Pregnancy

Aution Advised

Stability

  • Vitamin D Analogue

Contra Indications

  • Hypercalcaemia, Vit D Toxicity.

Precautions

  • Hypercalcaemia, Vit D Toxicity.

Lactation

  • Not Recommended.

Side Effects

  • Symptoms Of Vit D Toxicity. Hypercalcaemia. Rarely
  • Hypersensitivity.

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