Cefaclor

Therapeutic Group

Other Beta-Lactam, Cephalosporins & Penems

Indication Dosage

Susceptible Infections Due To Sensitive Gram-positive And Gram-negative Bacteria: 
Immediate-Release Medicines: 

  • Adult: 250 Mg 3 Times A Day; Maximum 4 G Per Day. 
  • Children 1-11 Months: 20 Mg/kg Daily In 3 Divided Doses, Alternatively 62.5 Mg 3 Times A Day; 
  • Children 1-4 Years: 20 Mg/kg Daily In 3 Divided Doses, Alternatively 125 Mg 3 Times A Day; 
  • Child 5-11 Years: 20 Mg/kg Daily In 3 Divided Doses, Usual Max. 1 G Daily, Alternatively 250 Mg 3 Times A Day; 
  • Children 12-17 Years: Same As Adult. 

In Severe Infection: Double The Dose 

Sustained - Release Tab: 

  • Adult & Children Above 12 Yrs: 375 Mg Every 12 Hours, Dose To Be Taken With Food 

Pneumonia: 

Sustained -Release Tab: 

  • Adult & Children Above 12 Yrs: 750 Mg Every 12 Hours, Dose To Be Taken With Food 

Urinary-tract Infections: 

Sustained-Release Tab: 

  • Adult & Children Above 12 Yrs: 375 Mg Every 12 Hours, Dose To Be Taken With Food 

Asymptomatic Carriage Of Haemophilus Influenzae Or Mild Exacerbations In Cystic Fibrosis: 

Immediate-Release Medicines: 

  • Children 1-11 Months: 125 Mg Every 8 Hours; 
  • 1-6 Years: 250 Mg 3 Times A Day; 
  • 7-17 Years: 500 Mg 3 Times A Day

Content

  • Tab /Cap 250mg /500mg: Cefaclor 250mg /500mg (as Monohydrate).
  • Tab 375mg /500mg /750mg: Cefaclor 375mg /500mg /750mg (as Monohydrate); Sustained Release Tab .
  • Drop Per ml: Cefaclor 50mg (as Monohydrate).

Pregnancy

No Evidence Of Harm

Stability

  • Antibacterials
  • Cephalosporins

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Caution Advised

Side Effects

  • Abdominal Discomfort
  • Agranulocytosis
  • Allergic Reactions
  • Anaphylaxis
  • Aplastic Anaemia
  • Blood Disorders
  • Confusion
  • Disturbances In Liver Enzymes
  • Dizziness
  • Eosinophilia
  • Haemolytic Anaemia
  • Hallucinations
  • Headache
  • Hypertonia
  • Leucopenia
  • Nervousness
  • Pruritus
  • Rashes
  • Fever And Arthralgia
  • Sleep Disturbances
  • Urticaria
  • Gi Disturbances
  • Rare: Stevens-johnson Syndrome
  • Thrombocytopenia
  • Toxic Epidermal Necrolysis
  • Transient Cholestatic Jaundice
  • Transient Hepatitis

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