Cetuximab

Therapeutic Group

Anti-neoplastics

Indication Dosage

Indication:

Cetuximab is a medication used to treat certain types of cancer. It is typically prescribed for:

  1. Colorectal Cancer: Cetuximab is used in combination with other treatments to slow down or stop the growth of colorectal cancer that has spread to other parts of the body.
  2. Head and Neck Cancer: It can also be used to treat head and neck cancer, particularly when other treatments haven't been effective.

Cetuximab works by targeting specific proteins in cancer cells, which helps to slow down the cancer's growth. Your doctor will determine if it's the right treatment for you and will provide more details about how it should be used.

Dosage:

Treatment Of Wild-type Ras Metastatic Colorectal Cancer In Patients With Tumours Expressing Epidermal Growth Factor Receptor, As Combination Therapy, Or As Monotherapy, Locally Advanced Squamous Cell Cancer Of The Head And Neck In Combination With Radiotherapy Or Platinum-based Chemotherapy: 

By IV Infusion: 

  • Adults: Initially400 Mg/1v Iv Infusion Over 120 Min. Maintenance: 250 Mg/ Mu Iv Infusion Over 60 Min Once Weekly. Max Infusion Rate: 5 Ml/min. 
  • Children: Not Recommended.

Content

  • Inj: Per ml: Cetuximab 5mg; 20 ml Vial.

Pregnancy

Positive Evidence Of Risk: Avoid

Stability

  • Monoclonal Antibody

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Contraindicated. Discontinue Breast-feeding.

Side Effects

  • Aseptic Meningitis
  • Blepharitis
  • Bronchospasm
  • Chills
  • Conjunctivitis
  • Desquamation
  • Diarrhoea
  • Dizziness
  • Dry Skin
  • Dyspnea
  • Fever
  • Headache
  • Hypertension
  • Hypertrichosis
  • Hypocalcaemia
  • Hypomagnesaemia
  • Hypotension
  • Infusion-related Reactions
  • Keratitis
  • Nail Disorders
  • Nausea
  • Pruritus
  • Rash
  • Severe Hypersensitivity Reactions
  • Shock
  • Skin Reactions
  • Urticaria
  • Vomiting.
  • Rare: Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis

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