Chloroquine Phosphate

Therapeutic Group

Anti-malarials

Indication Dosage

Chloroquine Phosphate is a medication primarily prescribed for the prevention and treatment of malaria, a potentially life-threatening mosquito-borne disease. It is also used in the management of certain autoimmune conditions like rheumatoid arthritis and lupus erythematosus. Chloroquine Phosphate works by interfering with the growth and reproduction of the malaria parasite within the red blood cells, effectively suppressing the infection. Additionally, it exhibits anti-inflammatory properties, which make it beneficial in alleviating symptoms associated with autoimmune disorders.

Malaria Suppressive: 

Oral: 

  • Adults: 500 Mg At Weekly Intervals. 
  • Children: 5 Mg/kg (as Chloroquine Base) At Weekly Intervals. 

Malaria Therapeutic: 

  • Oral: Adults: 1000 Mg Initially Then 500 Mg Daily. 

Hepatic Amoebiasis: 

  • Oral: Adults: 500-1000 Mg Daily. 

Cerebral Malaria: 

  • By IM Or IV Inj: Adults: 200-300 Mg (chloroquine Base)

Content

  • Inj: Per 5 ml: Chloroquine Phosphate 200mg (chloroquine Base 124mg).
  • Syp: Per 5 ml: Chloroquine Phosphate 68mg (chloroquine Base 50mg).
  • Tab 80mg /250mg: Chloroquine Phosphate 80mg (chloroquine)

Pregnancy

Use Only If Potential Benefit Outweighs Risk.

Stability

  • 4-Aminoquinoline

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Contraindicated or Not Recommended.

Side Effects

  • Abdominal Pain
  • Diarrhoea
  • Headache
  • Fever
  • Gi Distress
  • Blood Dyscrasias
  • Skin Rash (discontinue Immediately)
  • Blood Disorders
  • Skin Eruptions
  • Skin-pigmentation
  • Hair Loss
  • Blurred Vision
  • Corneal Opacities
  • Retinal Damage

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