Crizotinib
Therapeutic Group
Anti-neoplasticsIndication Dosage
Indication:
Crizotinib is a medication used to treat certain types of cancer, specifically for people with lung cancer that has a specific genetic mutation called ALK (anaplastic lymphoma kinase) or ROS1 (c-ros oncogene 1). It helps stop the cancer from growing and spreading in the body. Your doctor may prescribe Crizotinib if you have one of these genetic mutations and lung cancer to help control the disease and improve your quality of life.
Dosage:
Anaplastic Lymphoma Kinase (ALK)-positive Advanced Non-small Cell Lung Cancer, Ros1-positive Advanced Non-small Cell Lung Cancer:
- Adult: 250 Mg Twice Daily, Consult Product Literature For Information On Dose Adjustments
Content
- Cap 250mg: Crizotinib 250mg
Pregnancy
Avoid
Stability
- Antineoplastic, Protein Kinase Inhibitor
Contra Indications
- Gastrointestinal Perforation
Precautions
- Gastrointestinal Perforation
Lactation
- Avoid. Discontinue Breast-feeding.
Side Effects
- Anaemia
- Arrhythmias
- Constipation
- Diarrhoea
- Dizziness
- Fatigue
- Gait Abnormal
- Gi Disorders
- Heart Failure
- Hepatic Function Abnormal
- Hypogonadism
- Hypophosphataemia
- Leucopenia
- Local Swelling
- Movement Disorders
- Muscle Atrophy
- Muscle Tone Decreased
- Muscle Weakness
- Nausea
- Nerve Disorders
- Neuralgia
- Neurotoxicity
- Neutropenia
- Oedema
- Periorbital Oedema
- Peroneal Nerve Palsy
- Pulmonary Oedema
- Qt Interval Prolongation
- Renal Abscess
- Renal Cyst
- Respiratory Disorders
- Sensation Abnormal
- Skin Reactions
- Syncope
- Vision Disorders
- Vitreous Floater . Vomiting.
- Rare: Gi Perforation
- Hepatic Failure
- Renal Impairment