Diltiazem Hcl

Therapeutic Group

Calcium Channel Blockers

Indication Dosage

Prophylaxis And Treatment Of Angina: 

  • Adult: Initially 60 Mg 3 Times A Day, Adjusted According To Response; Maximum 360 Mg Per Day. Alternately, 90 Mg Sr Tab/cap Twice Daily; Increased If Necessary To 180 Mg Twice Daily 
  • Elderly: Initially 60 Mg Twice Daily, Adjusted According To Response; Maximum 360 Mg Per Day. Alternately, 90 Mg Sr Tab/cap Twice Daily 

Mild To Moderate Hypertension: 

  • Adult: 120 Mg Sr Tab/cap Twice Daily, Dose Form Not Appropriate For Initial Dose Titration

Content

  • Tab 30mg /60mg: Diltiazem Hci 30mg /60mg.
  • Retard Tab /Cap 90mg: Diltiazem Hci 90mg.
  • Sr Tab 60mg /90mg /120mg /180mg: Diltiazem Hci 60mg /90mg /120mg /180mg

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Calcium-channel Blockers

Contra Indications

  • Acute Porphyria, Left Ventricular Failure With Pulmonary Congestion, Severe Bradycardia, Sick Sinus Syndrome, 2nd Or 3rd Degree Av Block, Uncontrolled Cardiac Failure

Precautions

  • Acute Porphyria, Left Ventricular Failure With Pulmonary Congestion, Severe Bradycardia, Sick Sinus Syndrome, 2nd Or 3rd Degree Av Block, Uncontrolled Cardiac Failure

Lactation

  • Not Recommended.

Side Effects

  • Asthenia
  • Av Block
  • Bradycardia
  • Dizziness
  • Gi Disturbances
  • Headache
  • Hot Flushes
  • Hypotension
  • Malaise
  • Oedema (notably Of Ankles)
  • Palpitation
  • Sino-atrial Block
  • Fatigue
  • Gum Hyperplasia
  • Changes In Liver Function
  • Depression
  • Extrapyramidal Symptoms
  • Gum Hyperplasia
  • Gynaecomastia
  • Hepatitis.
  • Rare: Erythema Multiforme
  • Exfoliative Dermatitis
  • Photosensitivity
  • Rashes

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