Duloxetine

Therapeutic Group

Anti-depressants

Indication Dosage

Indication:

Duloxetine is a medication that is used to help people with depression and anxiety feel better. It can also be prescribed for chronic pain conditions like fibromyalgia and nerve pain caused by diabetes. Duloxetine works by balancing chemicals in the brain that affect mood and pain. Your doctor may give you this medicine to improve your overall well-being and reduce discomfort.

Dosage:

Major Depressive Disorder: 

  • Adult: 60 Mg Once Daily 

Generalized Anxiety Disorder: 

  • Adult: Initially 30 Mg Once Daily, Increased If Necessary To 60 Mg Once Daily; Maximum 120 Mg Per Day 

Diabetic Neuropathy: 

  • Adult: 60 Mg Once Daily, Discontinue If Inadequate Response After 2 Months; Review Treatment At Least Every 3 Months, Maximum Dose To Be Given In Divided Doses; Maximum 120 Mg Per Day 

Moderate To Severe Stress Urinary Incontinence: 

  • Adult (Female): 40 Mg Twice Daily, Patient Should Be Assessed For Benefit And Tolerability After 2-4 Weeks, Alternatively Initially 20 Mg Twice Daily For 2 Weeks, This Can Minimise Side Effects, Then Increased To 40 Mg Twice Daily, The Patient Should Be Assessed For Benefit And Tolerability After 2-4 Weeks.

Content

  • Cap 20mg /30mg /40mg /60mg: Duloxetine Hci 20mg /30mg /40mg /60mg.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk

Stability

  • Serotonin and Noradrenaline Reuptake Inhibitor

Contra Indications

  • Hepatic Or Severe Renal Impairment, Narrow-angle Glaucoma.

Precautions

  • Hepatic Or Severe Renal Impairment, Narrow-angle Glaucoma.

Lactation

  • Contraindicated, Avoid

Side Effects

  • Abnormal Dreams
  • Anorexia
  • Anxiety
  • Bruxism
  • Decreased Appetite
  • Diarrhoea
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Dyspepsia
  • Fatigue
  • Flatulence
  • Headache
  • Hot Flush
  • Insomnia
  • Nausea
  • Nervousness
  • Palpitation
  • Paraesthesia
  • Pruritus
  • Sexual Dysfunction
  • Sweating
  • Tremor
  • Visual Disturbances
  • Vomiting
  • Weakness
  • Weight Changes
  • Dysphagia
  • Gastritis
  • Stomatitis
  • Halitosis
  • Hepatitis
  • Hypertension
  • Hypothyroidism
  • Movement Disorders
  • Muscle Twitching
  • Musculoskeletal Pain
  • Photosensitivity
  • Postural Hypotension
  • Raised Cholesterol
  • Syncope
  • Tachycardia
  • Taste Disturbance
  • Thirst
  • Urinary Disorders
  • Vertigo.
  • Rare: Mania
  • Angle-closure Glaucoma

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