Efavirenz
Therapeutic Group
Anti-virals For Systemic UseIndication Dosage
Efavirenz is a medication used to treat HIV infection. It helps control the virus and improve the immune system in people living with HIV.
Hiv Infection In Combination With Other Antiretroviral Drugs:
- Adult: 600 Mg Cap/Tab Once Daily, In Combination With Protease Inhibitor & /or Nucleoside Analogue Reverse Transcriptase Inhibitors (nrtis)
- Children Below 17 Yr 40 Kg: 600 Mg Once Daily;
- Less Than 40 Kg: 400 Mg Once Daily;
- 25 - 32.5 Kg: 350 Mg Once Daily,
- 20 - 25 Kg: 300 Mg Once Daily;
- 15 - 20 Kg: 250 Mg Once Daily;
- 13 - 15 Kg: 200 Mg Once Daily.
- Children 3 Yr: See Literature
Content
- Tab 200mg /600mg: Efavirenz 200mg /600mg.
- Cap 50mg /100mg /200mg: Efavirenz 50mg /100mg /200mg.
Pregnancy
Avoid, Use Only When No Safer Alternative Exists For A Serious Problem.
Stability
- Non-nucleoside Reverse Transcriptase Inhibitor
Contra Indications
- None Known
Precautions
- None Known
Lactation
- Contraindicated
Side Effects
- Abdominal Pain
- Abnormal Dreams
- Anxiety
- Depression
- Diarrhoea
- Dizziness
- Fatigue
- Headache
- Impaired Concentration
- Nausea
- Pruritus
- Rash
- Sleep Disturbances
- Stevens-johnson Syndrome
- Vomiting
- Osteonecrosis
- Raised Serum Cholesterol
- Amnesia
- Ataxia
- Blurred Vision
- Convulsions
- Flushing
- Gynaecomastia
- Hepatitis
- Hypersensitivity
- Mania
- Pancreatitis
- Psychosis
- Suicidal Ideation
- Tinnitus
- Tremor
- Vertigo.
- Rare: Hepatic Failure
- Photosensitivity
- Suicide