Enalapril Maleate

Therapeutic Group

Ace Inhibitor

Indication Dosage

Hypertension: 

Oral: 

  • Adult: Initially 5 Mg Once Daily, Lower Initial Doses May Be Required When Used In Addition To Diuretic Or In Renal Impairment; Maintenance 20 Mg Once Daily; Maximum 40 Mg Per Day 
  • Children 2-12 Yrs & Body-weight >20 Kg: Initially 100 Mcg/kg Once Daily, Monitor Blood Pressure Carefully For 1-2 Hr, Increased As Necessary Up To Max 1 Mg/kg Daily In 1-2 Divided Doses; 
  • 12-18 Yr: Initially 2.5 Mg Once Daily, Monitor Blood Pressure Carefully For 1-2 Hr, Usual Maintenance Dose 10-20 Mg Daily In 1-2 Divided Doses, Max 40 Mg Daily In 1-2 Divided Doses If Body-weight Over 50 Kg. 

By IV Inj: 

  • Adult: 2.5-5 Mg/day Then Increase As Required, The Usual Therapeutic Dose For Hypertension Is 10-40 Mg/day In 1-2 Divided Doses. 

Congestive Heart Failure: 

  • Adult: Initially 2.5 Mg Once Daily, Increased If Tolerated To 10-20 Mg Twice Daily, Dose To Be Increased Gradually Over 2-4 Weeks 

Prevention Of Symptomatic Heart Failure In Patients With Asymptomatic Left Ventricular Dysfunction: 

  • Adult: Initially 2.5 Mg Once Daily, Increased If Tolerated To 10-20 Mg Twice Daily, Dose To Be Increased Gradually Over 2-4 Weeks

Content

  • Tab 5mg /10mg /20mg: Enalapril Maleate 5mg /10mg /20mg.
  • Inj 1mg: Per ml: Enalapril Maleate 1mg.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Angiotensin-converting Enzyme (ace) Inhibitors

Contra Indications

  • Aortic Stenosis, Outflow Obstruction.

Precautions

  • Aortic Stenosis, Outflow Obstruction.

Lactation

  • Caution Advised

Side Effects

  • Asthenia
  • Blurred Vision
  • Depression
  • Dyspnoea
  • Alopecia
  • Anorexia
  • Arrhythmias
  • Confusion
  • Drowsiness
  • Dry Mouth
  • Flushing
  • Hyponatraemia
  • Ileus
  • Impotence
  • Insomnia
  • Muscle Cramps
  • Nervousness
  • Palpitation
  • Peptic Ulcer
  • Sweating
  • Tinnitus
  • Vertigo.
  • Rare: Abnormal Dreams
  • Allergic Alveolitis
  • Exfoliative Dermatitis
  • Glossitis
  • Gynaecomastia
  • Pemphigus
  • Pulmonary Infiltrates
  • Raynaud's Syndrome
  • Stevens-Johnson Syndrome
  • Stomatitis
  • Toxic Epidermal Necrolysis

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