Febuxostat

Therapeutic Group

Anti-Gout Preparations

Indication Dosage

Treatment Of Chronic Hyperuricaemia In Gout: 

  • Adult: Initially 80 Mg Once Daily, If After 2-4 Weeks Of Initial Dose, Serum Uric Acid is Greater Than 6 Mg/100ml Then Increase Dose; Increased If Necessary To 120 Mg Once Daily 

Prophylaxis And Treatment Of Acute Hyperuricaemia With Initial Chemotherapy For Haematologic Malignancies: 

  • Adult: 120 Mg Once Daily, To Be Started 2 Days Before Start Of Cytotoxic Therapy And Continued For 7-9 Days, According To Chemotherapy Duration

Content

  • Tab 40mg /80mg: Febuxostat 40mg /80mg

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Xanthine Oxidase Inhibitor

Contra Indications

  • Not A Treatment For Acute Gout But Continue If Attack Develops When Already Receiving Allopurinol, And Treat Attack Separately

Precautions

  • Not A Treatment For Acute Gout But Continue If Attack Develops When Already Receiving Allopurinol, And Treat Attack Separately

Lactation

  • Contraindicated

Side Effects

  • Abnormal Liver Function Tests
  • Gi Disturbances
  • Headache
  • Oedema
  • Rash
  • Renal Failure
  • Appetite Change
  • Arthralgia
  • Arthritis
  • Atrial Fibrillation
  • Bronchitis
  • Bursitis
  • Chest Pain
  • Cholelithiasis
  • Dermatitis
  • Diabetes Mellitus
  • Dizziness
  • Drowsiness
  • Dyspnea
  • Ecg Abnormalities
  • Erectile Dysfunction
  • Flushing
  • Haematuria
  • Hemiparesis
  • Hyperlipidaemia
  • Hypertension
  • Hypoaesthesia
  • Increased Thyroid Stimulating Hormone
  • Increased Urinary Frequency
  • Insomnia
  • Muscle Spasm
  • Muscle Weakness
  • Myalgia
  • Nephrolithiasis
  • Palpitation
  • Paraesthesia
  • Proteinuria
  • Taste Disturbances
  • Weight Change

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