Flucloxacillin
Therapeutic Group
Beta-Lactam Anti-bacterials, PenicillinsIndication Dosage
Infections Due To Beta-lactamase-producing Staphylococci Including Respiratory Tract, Ent, Ut, And Soft Tissue Infections, Gonorrhoea, Dental Abscess, Otitis Externa, Adjunct In Pneumonia, Impetigo And Cellulitis:
Oral:
- Adult: 250-500 Mg 4 Times A Day;
- Children 1 Month-1 Year: 62.5-125 Mg 4 Times A Day;
- 2-9 Years: 125-250 Mg 4 Times A Day;
- 10-17 Years: 250-500 Mg 4 Times A Day
By IM Inj:
- Adult: 250-500 Mg Every 6 Hours
By Slow IV Inj, Or IV Infusion:
- Adult: 0.25-2 G Every 6 Hours
Endocarditis (in Combination):
By Slow IV Inj, Oriv Infusion:
- Adult: (body-weight Up To 85 Kg): 8 G Daily In 4 Divided Doses; (body-weight 85 Kg And Above): 12 G Daily In6 Divided Doses
Osteomyelitis:
By Slow IV Inj, Or IV Infusion:
- Adult: Up To 8 G Daily In 3-4 Divided Doses
Surgical Prophylaxis:
By Slow IV Inj, Or IV Infusion:
- Adult: 1-2 G, To Be Administered Up To 30 Minutes Before The Procedure, Then (by Mouth Or By IM Injection Or By Slow IV Injection Or By IV Infusion) 500 Mg Every 6 Hours If Required For Up To 4 Further Doses In High Riskprocedures
Staphylococcal Lung Infection In Cystic Fibrosis:
Oral:
- Child: 25 Mg/kg 4 Times A Day (max. Per Dose 1 G), Alternatively 100 Mg/kg Daily In 3 Divided Doses; Maximum 4 G Per Day
Content
- Cap 250mg /500mg: Flucloxacillin 250mg /500mg.
- Inj 250mg /500mg: Flucloxacillin 250mg / 500mg; Vial.
- Syp: Per 5 ml: Flucloxacillin 125mg.
Pregnancy
Use Only If Essential
Stability
- Penicillinase-resistant Penicillin
Contra Indications
- History Of Flucloxacillin Associated Jaundice/hepatic Dysfunction, Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.
Precautions
- History Of Flucloxacillin Associated Jaundice/hepatic Dysfunction, Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.
Lactation
- Caution Advised
Side Effects
- Hypersensitivity Reactions
- Gi Disturbane
- Super Infection
- hepatic Reactions.
- Rare: Pseudomembranous Colitis
- Erythema Multiforme
- Stevens-johnson Syndrome
- Toxic Epidermal Necrolysis.