Flurbiprofen

Therapeutic Group

Anti-inflammatory And Anti-rheumatic Products

Indication Dosage

Pain And Inflammation In Rheumatic Disease And Other Musculoskeletal Disorders, Migraine, Postoperative Analgesia, Mild To Moderate Pain: 

  • Adult & Children Above 12 Yrs: 150-200 Mg Daily In 2-4 Divided Doses, Then Increased To 300 Mg Daily, Dose To Be Increased Only In Acute Conditions 

Dysmenorrhoea: 

  • Adult & Children Above 12 Yrs: Initially 100 Mg, Then 50-100 Mg Every4-6 Hours; Maximum 300 Mg Per Day

Content

  • Sr Cap 200mg: Flurbiprofen 200mg; Sustained-Release Capsules.
  • Tab 50mg /100mg: Flurbiprofen 50mg /100mg.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Propionic Acid

Contra Indications

  • Active Or Recurrent Gi Bleeding Or Ulceration, Cerebrovascular Disease, History Of Gi Bleeding Or Gi Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment, Aspirin/anti-inflammatory In-duced Allergy.

Precautions

  • Active Or Recurrent Gi Bleeding Or Ulceration, Cerebrovascular Disease, History Of Gi Bleeding Or Gi Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment, Aspirin/anti-inflammatory In-duced Allergy.

Lactation

  • Contraindicated or Not Recommended.

Side Effects

  • Angioedema
  • Blood Disorders
  • Bronchospasm
  • Colitis
  • Crohn's Disease
  • Depression
  • Diarrhoea
  • Dizziness
  • Drowsiness
  • Fluid Retention
  • Gi Bleeding And Ulceration
  • Gi Disturbances
  • Haematuria
  • Headache
  • Hearing Disturbances
  • Hypersensitivity Reactions
  • Insomnia
  • Nausea
  • Nervousness
  • Photosensitivity
  • Raised Blood Pressure
  • Rashes
  • Renal Failure (especially In Patients With Preexisting Renal Impairment)
  • tinnitus
  • Vertigo.
  • Rare: Hepatic Damage
  • Interstitial Fibrosis Associated With Nsaids
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis
  • Visual Disturbances
  • Local Irritation With Use Of Rectal Suppositories