Furosemide

Therapeutic Group

Diuretic

Indication Dosage

Furosemide is a medication primarily indicated for the treatment of edema, a condition characterized by the accumulation of excess fluid in the body, often associated with congestive heart failure, kidney disorders, or liver disease. It is also used to manage hypertension (high blood pressure). Furosemide works by increasing urine production, thereby helping the body eliminate excess salt and water, which in turn reduces swelling and lowers blood pressure.

Oedema: 

Oral: 

  • Adult: Initially 40 Mg Daily In The Morning, Then Maintenance 20-40 Mg Daily  

By IM Inj, By Slow IV Inj, Or By IV Infusion: 

  • Adult: Initially 20-50 Mg, Increased In Steps Of 20 Mg Every 2 Hours If required, Doses Greater Than 50mg Given By IV Infusion Only; Maximum 1.5 G Per Day 

Resistant Oedema: 

Oral: 

  • Adult: 80-120 Mg Daily 

By IM Inj, By Slow IV Inj, Or By IV Infusion: 

  • Adult: Initially 20-50 Mg, Increased In Steps Of 20 Mg Every 2 Hours If required, Doses Greater Than 50mg Given By IV Infusion Only; Maximum 1.5 G Per Day 

Resistant Hypertension: 

  • Adult: 40-80 Mg Daily 

By IM Inj, By Slow IV Inj, Or By IV Infusion: 

  • Adult: Initially 20-50 Mg, Increased In Steps Of 20 Mg Every 2 Hours If required, Doses Greater Than 50mg Given By IV Infusion Only; Maximum 1.5 G Per Day 

Heart Failure: 

By IM Inj, Or By Slow IV Inj: 

  • Adults: 20-40 Mg. May Repeat Or Increase By 20 Mg After 2 Hr. 
  • Children: 1 Mg/kg Single Dose. May Increase By 1 Mg/kg After 2 Hr. Max: 6 Mg/kg Administration: IV Injections Should Be Given Slowly Over 1-2 Min; Maximum Rate Of Administration For Ivpb Or Infusion: 4 Mg/min; Replace Parenteral Therapy With Oral Therapy As Soon As Possible. In Chf And Chronic Renal Failure: It Has Been Suggested That Doses As High As 2 To 2.5 Gm/day Or More Are Well Tolerated And Effective In These Patients. For IV bolus Injection, The Maximum Dose Should Not Exceed 1 Gm/day Given Over 30 Min. IV infusion Solution Mixed In Ns Or D5w Solution Is Stable For 24 Hours At Room Temperature.

Content

  • Tab 20mg /40mg: Furosemide 20mg /40mg.
  • Liquid: Per 5 ml: Furosemide 40mg.
  • Inj: Per 2 ml: Furosemide 20mg.
  • Syp: Per 5 ml: Furosemide 5mg.

Pregnancy

Caution Advised

Stability

  • Loop Diuretic

Contra Indications

  • Renal Failure With Anuria, Hepatic Coma, Hypokalaemia, Hyponatraemia, Hypotension, Hypersensitivity To Sulphonamides, In Pregnancy For Short Time And If Strictly Indicated.

Precautions

  • Renal Failure With Anuria, Hepatic Coma, Hypokalaemia, Hyponatraemia, Hypotension, Hypersensitivity To Sulphonamides, In Pregnancy For Short Time And If Strictly Indicated.

Lactation

  • Caution Advised

Side Effects

  • Disorders Of Electrolyte Balance
  • Dehydration
  • Allergic Reactions
  • Gout
  • Intrahepatic Cholestasis

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