Gemcitabine

Therapeutic Group

Anti-neoplastics

Indication Dosage

Gemcitabine is a medication used to treat certain types of cancer. It's often prescribed for cancers like pancreatic cancer, lung cancer, and breast cancer. Gemcitabine helps slow down the growth of cancer cells and can be an important part of cancer treatment plans. Your doctor will determine if it's the right option for your specific type of cancer.

First-line Treatment For Locally Advanced Or Metastatic Non-small Cell Lung Cancer As Monotherapy In Elderly Patients And In Palliative Treatment Or In Combination With Cisplatin: 

By IV Infusion: 

  • Adults & Elderly: 1000 Mg/m2 Over 30 Min On Days 1,8 &15; Repeat Every 28 days or 1250 Mg/m2 Over 30 Min On Days 1,8; Repeat Every 21 Days. 

Treatment Of Locally Advanced Or Metastatic Pancreatic Cancer, Advanced Or Metastatic Bladder Cancer (in Combination With Cisplatin), Locally Advanced Or Metastatic Epithelial Ovarian Cancer Which Has Relapsed (in Combination With Carboplatin), Metastatic Breast Cancer Which Has Relapsed After Previous Chemotherapy (in Combination With Paclitaxel): 

By IV Infusion: 

  • Adults: 1000 Mg/m2 Over 30 Min Wkly For 3 Or 7 Wk Followed By 1 Wk Rest; Repeat Cycles 3 Out Of Every 4 Wk

Content

  • Inj 100mg /200mg /500mg /1gm /2gm: Gemcitabine (as Hci) 100mg /200mg /500mg /1gm /2gm; Powder In Vial.

Pregnancy

Positive Evidence Of Risk: Avoid

Stability

  • Antimetabolite

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Contraindicated. Discontinue Breast-feeding.

Side Effects

  • Alopecia
  • Bone-marrow Suppression
  • Extravasation
  • Hyperuricaemia
  • Influenza-like Symptoms
  • Microangiopathic Haemolytic Anaemia
  • Musculoskeletal Pain
  • Nausea
  • Oralmucositis
  • Pulmonary Toxicity
  • Rash
  • Renal Impairment
  • Thromboembolism
  • Tumourlysis Syndrome
  • Vomiting
  • Rare: Haemolytic Uraemic Syndrome