Hepatitis B Immunoglobulin

Therapeutic Group

Immune Sera And Immunoglobulins

Indication Dosage

Hepatitis B Immunoglobulin, often called Hepatitis B IG, is used to protect people from getting infected with the Hepatitis B virus. It's given to individuals who have been exposed to Hepatitis B, like through a needlestick injury or close contact with an infected person, to help prevent the virus from causing an infection in their body. Essentially, it acts as a shield against Hepatitis B when you might be at risk.

Prophylaxis Against Hepatitis B Infection For Individuals Exposed To The Hepatitis B Virus: 

By IM Inj: 

  • Adult: 500 Units, Dose To Be Administered As Soon As Possible After Exposure; Ideally Within 12-48 Hours, But No Later Than 7 Days After Exposure 

Prevention Of Hepatitis B Re-infection More Than 6 Months After Liver Transplantation In Stable Hbv-DNA Negative Patients: 

By Sc Inj: 

  • Adult (body weight Up To 75 Kg): 500 Units Once Weekly, Increased If Necessary Up To 1000 Units Once Weekly; 
  • (body weight 75 Kg And Above): 1000 Units Once Weekly, Dose To Be Started 2-3 Weeks After Last Dose Of Intravenous Hepatitis B Immunoglobulin 

Prevention Of Hepatitis B In Haemodialysed Patients, Prophylaxis Against Re-infection Of Transplanted Liver: 

By IV Infusion: 

  • Adult: (consult Product Literature) 

Perinatal Exposure Of Infants Born To Hbs Ag-Positive Mothers: 

  • Neonate: 0.5 Ml To Infants Within 12 Hr After Birth.

Content

  • Per ml: Hepatitis B Immune Globulin (human) 200 Iu;
  • Inj: Per ml: Hepatitis B Immune Globulin (human) 217 Iu, Glycine; 0.5 ml, 1 ml, 5 ml Vial

Pregnancy

Consult with Doctor Or Caution Advised

Stability

  • Immunoglobulin

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Consult with Doctor Or Caution Advised

Side Effects

  • Injection Site Reactions
  • Abdominal Pain
  • Anaphylaxis
  • Arthralgia
  • Buccal Ulceration
  • Chest Pain
  • Dizziness
  • Dyspnea
  • Glossitis
  • Headache
  • Tremor Side-effects With Iv Use: Abdominal Distension
  • Blood Pressure Fluctuations
  • Deep Vein Thrombosis
  • Haemolytic Anaemia
  • Injection Site Reactions
  • Myocardial Infarction
  • Pulmonary Embolism
  • Stroke
  • Thromboembolic Events