Hydroxyethyl Starch

Therapeutic Group

Blood Substitutes And Plasma Protein Fractions

Indication Dosage

Hydroxyethyl starch (HES) is a colloid solution that is commonly used as a volume expander in the treatment of hypovolemia (low blood volume) caused by a variety of conditions. Some common indications of HES infusion include:

  1. Hypovolemia due to hemorrhage or other causes
  2. Septic shock or other forms of shock
  3. Burn injuries
  4. Surgical procedures, especially those involving major blood loss
  5. Management of intracranial pressure in patients with traumatic brain injury or cerebral edema

The ingredients included in hydroxyethyl starch (HES) solution.

  • Hydroxyethyl starch: This is the active ingredient and is a polymer derived from cornstarch or potato starch. It is used as a plasma volume expander to increase blood volume and maintain blood pressure.
  • Sodium chloride: This is a salt that is used to maintain the electrolyte balance in the body.
  • Calcium chloride: This is a salt that is used to maintain the electrolyte balance in the body and to prevent coagulation problems.
  • Potassium chloride: This is a salt that is used to maintain the electrolyte balance in the body and to prevent muscle weakness and cramping.
  • Magnesium chloride: This is a salt that is used to maintain the electrolyte balance in the body and to prevent muscle weakness and cramping.
  • Water for injection: This is a sterile water that is used as a solvent to dissolve the other ingredients and make the HES solution.

Content

  • 1000ml Solution: Hydroxyethyl Starch

Pregnancy

Caution Advised

Stability

  • Plasma Substitute

Contra Indications

  • contraindicated in patients with severe bleeding or hypersensitivity to HES or its components.

Precautions

  • contraindicated in patients with severe bleeding or hypersensitivity to HES or its components.

Lactation

  • Caution Advised

Side Effects

  • Fluid overload and edema
  • Coagulopathy and bleeding
  • Kidney damage
  • Anaphylactic reactions
  • Electrolyte imbalances
  • Pruritus and skin rash
  • Increased risk of infections
  • Hemodynamic instability