Hydroxyethyl Starch
Therapeutic Group
Blood Substitutes And Plasma Protein FractionsIndication Dosage
Hydroxyethyl starch (HES) is a colloid solution that is commonly used as a volume expander in the treatment of hypovolemia (low blood volume) caused by a variety of conditions. Some common indications of HES infusion include:
- Hypovolemia due to hemorrhage or other causes
- Septic shock or other forms of shock
- Burn injuries
- Surgical procedures, especially those involving major blood loss
- Management of intracranial pressure in patients with traumatic brain injury or cerebral edema
The ingredients included in hydroxyethyl starch (HES) solution.
- Hydroxyethyl starch: This is the active ingredient and is a polymer derived from cornstarch or potato starch. It is used as a plasma volume expander to increase blood volume and maintain blood pressure.
- Sodium chloride: This is a salt that is used to maintain the electrolyte balance in the body.
- Calcium chloride: This is a salt that is used to maintain the electrolyte balance in the body and to prevent coagulation problems.
- Potassium chloride: This is a salt that is used to maintain the electrolyte balance in the body and to prevent muscle weakness and cramping.
- Magnesium chloride: This is a salt that is used to maintain the electrolyte balance in the body and to prevent muscle weakness and cramping.
- Water for injection: This is a sterile water that is used as a solvent to dissolve the other ingredients and make the HES solution.
Content
- 1000ml Solution: Hydroxyethyl Starch
Pregnancy
Caution Advised
Stability
- Plasma Substitute
Contra Indications
- contraindicated in patients with severe bleeding or hypersensitivity to HES or its components.
Precautions
- contraindicated in patients with severe bleeding or hypersensitivity to HES or its components.
Lactation
- Caution Advised
Side Effects
- Fluid overload and edema
- Coagulopathy and bleeding
- Kidney damage
- Anaphylactic reactions
- Electrolyte imbalances
- Pruritus and skin rash
- Increased risk of infections
- Hemodynamic instability