Ifosfamide
Therapeutic Group
Anti-neoplasticsIndication Dosage
Ifosfamide is prescribed to treat certain types of cancer, such as testicular cancer, ovarian cancer, and soft tissue sarcomas. It is often used in combination with other medications as part of cancer chemotherapy to help slow down or stop the growth of cancer cells.
Malignant Disease:
By IV Infusion:
- Adult: 1.2 Gm/m2/ Day IV for 5 Days. Repeat Every 3 Wk.
Content
- Inj 500mg /1gm /2gm: Ifosfamide 500mg /1gm /2gm; Vial.
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
- Alkylating Agent
Contra Indications
- Severe Bone Marrow Suppression, Acute Infection, Urinary-tract Infection, Urinary-tract Obstruction, Urothelial Damage
Precautions
- Severe Bone Marrow Suppression, Acute Infection, Urinary-tract Infection, Urinary-tract Obstruction, Urothelial Damage
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Confusion
- Disorientation
- Drowsiness
- Psychosis
- Renal Toxicity (may Lead To Tubular Dysfunction
- Fanconi's Syndrome
- Or Diabetes Insipidus)
- Restlessness
- Urothelial Toxicity
- Severe Encephalopathy
- Acute Pancreatitis
- Alopecia
- Arrhythmias
- Bone-marrow Suppression
- Extravasation
- Heart Failure
- Hyperuricaemia
- Male Sterility
- Nausea
- Oralmucositis
- Premature Menopause
- Secondary Malignancy
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting.
- Rare: Anorexia
- Constipation
- Convulsions
- Diarrhoea