Irbesartan And Hydrochlorothiazide

Therapeutic Group

Angiotensin-ii Antagonists, Combinations

Indication Dosage

Hypertension Not Adequately Controlled With Irbesartan Alone: 

  • Adults: 1 Tab Daily Max Daily Dose; 300 Mg Irbesar-tan & 25 Mg Hydrochlorothiazide. 
  • Children: Not Recommended.

Content

  • Tab 150 /12.5mg: irbesartan 150mg, Hydrochlorothiazide 12.5mg.
  • Tab 300 /12.5mg: irbesartan 300mg, Hydrochlorothiazide 12.5mg.
  • Tab 300 /25mg: irbesartan 300mg, Hydrochlorothiazide 25mg

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Angiotensin II Antagonist
  • Thiazide Diuretic

Contra Indications

  • Severe Renal Or Hepatic Impairment; Refractory Hyperkalaemia, Hypercalcaemia; Biliary Cirrhosis Or Cholestasis.

Precautions

  • Severe Renal Or Hepatic Impairment; Refractory Hyperkalaemia, Hypercalcaemia; Biliary Cirrhosis Or Cholestasis.

Lactation

  • Not Recommended.

Side Effects

  • Hyperkalaemia
  • Angioedema
  • Symptomatic Hypotension Including Dizziness Particularly In Patients With Intravascular Volume Depletion
  • E.g. Those Taking High-dose Diuretics
  • Arthralgia
  • Rhinitis
  • Flatulence
  • Hypertriglyceridaemia
  • Musculoskeletal Trauma
  • Nausea/vomiting
  • Abnormal Urination.

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