Lansoprazole

Therapeutic Group

Peptic Ulcer & Gastro-Oesophageal Reflux Disease

Indication Dosage

Helicobacter Pylori Eradication:

  • Adult: 30 Mg Twice Daily. Used In Combination With Amoxicillin And Clarithromycin, In Combination with Withamoxicillin And Metronidazole, Or In Combination with Withclarithromycin And Metronidazole.

Benign Gastric Ulcer:

  • Adult: 30 Mg Once Daily For 8 Weeks, Dose To Be Taken In The Morning

Duodenal Ulcer:

  • Adult: 30 Mg Once Daily For 4 Weeks, Dose To Be Taken In The Morning; Maintenance 15 Mg Once Daily

Nsaid-associated Duodenal Ulcer, Nsaid-associated Gastric Ulcer:

  • Adult: 30 Mg Once Daily For 4 Weeks, Continued For Further 4 Weeks If Not Fully Healed

Prophylaxis Of Nsaid-associated Duodenal/gastric Ulcer:

  • Adult: 15-30 Mg Once Daily

Zollinger-Ellison Syndrome (and Other Hypersecretoryconditions):

  • Adult: Initially 60 Mg Once Daily, Adjusted According To Response, Daily Doses Of 120 Mg Or More Given In Two Divided Doses

Gastro-oesophageal Reflux Disease:

  • Adult: 30 Mg Once Daily For 4 Weeks, Continued For Further 4 Weeks If Not Fully Healed; Maintenance 15-30 Mg Once Daily, Doses To Be Taken In The Morning.

Acid-related Dyspepsia, Gi Bleeding:

  • Adult: 15-30 Mg Once Daily For 2-4 Weeks, Doses To Be Taken In The Morning
  • Children: Not Recommended.

By Iv Inj: For Patients Who Are Unable To Take Oral Dosage.

  • Adults: Iv 30 Mg Daily For Up To 7 Days

Content

  • Cap 15 mg/ 30 mg: Lansoprazole 15 mg/ 30 mg.
  • Tab 15 mg/ 30 mg: Lansoprazole 15 mg/ 30 mg.
  • Inj 30 mg: Lansoprazole 30 mg; Powder In Vial.

Pregnancy

No Evidence Of Risk, Advised To Avoid

Stability

  • Proton Pumps Inhibitor (PPI)

Contra Indications

  • Malignancy, Severe Hepatic Impairment.

Precautions

  • Malignancy, Severe Hepatic Impairment.

Lactation

  • Not Recommended

Side Effects

  • Epidermal Necrolysis
  • Atrophic Gastritis
  • Pruritus
  • Headache
  • Dizziness
  • Fatigue
  • Malaise
  • Gi Disturbances
  • Sore Throat
  • Skin Irritation
  • Liver Disorders
  • Risk Of Gi Infection.
  • Rarely Arthralgia
  • Myalgia
  • Peripheral Oedema
  • Erythematous Or Bullous Rashes
  • Haematological Changes
  • Stevens-johnson Syndrome
  • Intestinal Nephritis
  • Depression
  • Confusion
  • Hallucinations
  • Gynaecomastia
  • Impotence.