Levofloxacin

Therapeutic Group

Quinolone Anti-bacterials

Indication Dosage

Acute Sinusitis: 

Oral: 

  • Adult: 500 Mg Once Daily For 10-14 Days 

Acute Exacerbation Of Chronic Bronchitis: 

Oral:

  • Adult: 500 Mg Once Daily For 7-10 Days 

Community-acquired Pneumonia, Nosocomial Pneumonia: 

Oral: 

  • Adult: 500-750 Mg 1-2 Times A Day For 7-14 Days 

By IV Infusion: 

  • Adult: 500 Mg 1-2 Times A Day, To Be Given Over At Least60 Minutes For 7-14 Days 

Urinary-tract Infections: 

Oral: 

  • Adult: 500 Mg Once Daily For 7-14 Days 

Urinary tract Infections (uncomplicated): 

Oral: 

  • Adult: 250 Mg Once Daily For 3 Days 

Complicated urinary tract Infections, Acute Pyelonephritis: 

By IV Infusion: 

  • Adult: 500 Mg Once Daily, To Be Given Over At Least 60 Minutes 

Chronic Prostatitis: 

Oral: 

  • Adult: 500 Mg Once Daily For 28 Days 

By IV Infusion: 

  • Adult: 500 Mg Once Daily, To Be Given Over At Least 60 Minutes 

Complicated Skin Infections, Complicated Soft-tissue Infections: 

Oral: 

  • Adult: 500-750 Mg 1-2 Times A Day For 7-14 Days 

By IV Infusion: 

  • Adult: 500-750 Mg 1-2 Times A Day, To Be Given Over At Least 60 Minutes 

Inhalation Of Anthrax (treatment And Post-exposure Prophylaxis): 

Oral: 

  • Adult: 500 Mg Once Daily For 8 Weeks 

By IV Infusion: 

  • Adult: 500 Mg Once Daily, To Be Given Over At Least 60 Minutes 

Lower Respiratory Infection, Upper Respiratory Infection, Sinusitis: 

Oral: 

  • Adult: 500 Mg Once Daily For 7-14 Days Or 750 Mg Once Daily For 5 Days. 

By IV Infusion: 

  • Adult: 500-750 Mg Once Daily, To Be Given Over At Least 60 Minutes For 5-7 Days 
  • Children: Not Recommended.

Content

  • Cap /Tab 250mg /500mg /750mg: Levofloxacin (as Levofloxacin Hemihydrate) 250mg /500mg /750mg.
  • Inj 250mg /500mg: Per ml: Levofloxacin 2.5mg /5mg; Solution.

Pregnancy

Contraindicated

Stability

  • Fluoroquinolone Antibiotic

Contra Indications

  • Hypersensitivity To Levofloxacin Or Ofloxacin, Tendon Disorders.

Precautions

  • Hypersensitivity To Levofloxacin Or Ofloxacin, Tendon Disorders.

Lactation

  • Contraindicated

Side Effects

  • Diarrhoea
  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Abdominal Pain
  • Anorexia
  • Anxiety
  • Arthralgia
  • Asthenia
  • Blood Disorders
  • Confusion
  • Depression
  • Disturbances In Taste
  • Hearing
  • Smell And Vision
  • Dyspepsia
  • Eosinophilia
  • Hallucinations
  • Leucopenia
  • Myalgia
  • Rash
  • Sleep Disturbances
  • Thrombocytopenia
  • Tremor.
  • Rare: Antibiotic-associated Colitis
  • Convulsions
  • Dyspnea
  • Hepatic Dysfunction
  • Hepatitis
  • Hypotension
  • Interstitial Nephritis
  • Jaundice
  • Photosensitivity
  • Psychoses
  • Renal Failure
  • Symptoms Of Peripheral Neuropathy
  • Tendon Damage And Inflammation (discontinue)
  • Vasculitis
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis

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