Lorazepam

Therapeutic Group

Psycholeptics (Antipsychotic, Anxiolytic/Hypnotic)

Indication Dosage

Lorazepam is a medication used to help people who are feeling very anxious or having trouble sleeping. It can also be used before certain medical procedures to help you relax.

Short-term Use In Anxiety: 

  • Adult: 1-4 Mg Daily In Divided Doses, For Debilitated Patients, Use Elderly Dose 
  • Elderly: 0.5-2 Mg Daily In Divided Doses 

Short-term Use In Insomnia Associated With Anxiety: 

  • Adult: 1-2 Mg Daily, To Be Taken At Bedtime 

Conscious Sedation For Procedures: 

  • Adult: 2-3 Mg, To Be Taken The Night Before Operation; 2-4 Mg, To Be Taken 1-2 Hours Before Operation 

Premedication: 

  • Adult: 2-3 Mg, To Be Taken The Night Before Operation; 2-4 Mg, To Be Taken 1-2 Hours Before Operation

Content

  • Tab 1mg /2mg: Lorazepam 1mg /2mg.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk

Stability

  • Benzodiazepine

Contra Indications

  • Chronic Psychosis, Cns Depression, Respiratory Depression, Compromised Airway, Hyperkinesis, Not For Use Alone To Treat Depression (or Anxiety Associated With Depression), Obsessional States, Phobic States, Acute Pulmonary Insufficiency, Severe Hepatic Impairment.

Precautions

  • Chronic Psychosis, Cns Depression, Respiratory Depression, Compromised Airway, Hyperkinesis, Not For Use Alone To Treat Depression (or Anxiety Associated With Depression), Obsessional States, Phobic States, Acute Pulmonary Insufficiency, Severe Hepatic Impairment.

Lactation

  • Contraindicated, Avoid

Side Effects

  • Amnesia
  • Ataxia (especially In The Elderly)
  • confusion
  • Dependence
  • Drowsiness
  • Lightheadedness
  • Muscle Weakness
  • Paradoxical Increase In Aggression
  • Dizziness
  • Dysarthria
  • Gi Disturbances
  • Gynaecomastia
  • Headache
  • Hypotension
  • Incontinence
  • Salivation Changes
  • Slurred Speech
  • Tremor
  • Urinary Retention
  • Vertigo
  • Visual Disturbances.
  • Rare: Apnoea
  • Blood Disorders
  • Respiratory Depression
  • Jaundice
  • Skin Reactions