Methylprednisolone Acetate

Therapeutic Group

Corticosteroids, Systemic Use

Indication Dosage

Anti-inflammatory Or Immunosuppressive: 

By IM Inj: 

  • Adult: 10-80 Mg Every 1-2 Week. 

Rheumatoid Arthritis: 

By Intra-articular Inj: 

  • Adult: Every 1-5 Weeks; Large Joints (e.g. Knee, Ankle): 20-80 Mg; Medium Joints (e.g. Elbow, Wrist): 10-40 Mg; Small Joints: 4-10 Mg. 

Acute Or Severe Dermatitis: 

By IM Inj: 

  • Adult: 80-120 Mg As A Single Dose. 

Chronic Dermatitis: 

By IM Inj: 

  • Adult: 40-120 Mg Every 5-10 Days. 

Keloid, Lichen Planus, And Other Dermatologic Conditions: 

By Intralesional Inj: 

  • Adult: 20-60 Mg.

Content

  • Inj: Per ml: Methylprednisolone Acetate 40mg; Vi-als Of 1 ml& 2 ml.

Pregnancy

Caution Advised

Stability

  • Glucocorticoid

Contra Indications

  • Systemic Fungal Infections Unless Specific Anti-infective Therapy Is Used, Head Injury, Stroke.

Precautions

  • Systemic Fungal Infections Unless Specific Anti-infective Therapy Is Used, Head Injury, Stroke.

Lactation

  • Caution Advised

Side Effects

  • Endocrine Irregularities Including Menstrual Problems
  • Cushingoid State
  • Adrenal Suppression
  • Growth Suppression In Children
  • Increased Susceptibility To Infection
  • Increased Severity Of Infection
  • Fluid/electrolyte Disturbance
  • Hypertension
  • Negative Protein
  • Nitrogen And Calcium Balance
  • Myopathy
  • Tendon Rupture
  • Osteoporosis
  • Osteonecrosis And Fractures
  • Impaired Wound Healing
  • Sweating
  • Hirsutism
  • Striae
  • Telangiectasia
  • Acne
  • Gi Disturbance
  • Peptic Ulceration
  • Acute Pancreatitis
  • Candidiasis
  • Psychiatric Effects
  • Neurological Effects
  • Insomnia
  • Diabetes
  • Impaired Glucose Tolerance
  • Weight Gain
  • Increased Appetite
  • Ocular Disturbances Including Cataracts
  • Raised In-traocular Pressure
  • Optic Nerve Damage
  • Corneal Changes
  • Glaucoma
  • Thromboembolism
  • Leukocytosis