Moxifloxacin

Therapeutic Group

Quinolone Anti-bacterials

Indication Dosage

Exacerbations Of Chronic Bronchitis: 

Oral: 

  • Adult: 400 Mg Once Daily For 5-10 Days 

Acute Sinusitis: 

Oral: 

  • Adult: 400 Mg Once Daily For 7 Days 

Community-acquired Pneumonia: 

Oral: 

  • Adult: 400 Mg Once Daily For 7-14 Days 

By IV Infusion: 

  • Adult: 400 Mg Once Daily For 7-14 Days, To Be Given Over 60 Minutes 

Mild To Moderate Pelvic Inflammatory Disease: 

Oral: 

  • Adult: 400 Mg Once Daily For 14 Days 

Complicated Skin And Soft-tissue Infections When Other Antibacterials Are Inappropriate Or Failed: 

Oral: 

  • Adult: 400 Mg Once Daily For 7-21 Days 

By IV Infusion: 

  • Adult: 400 Mg Once Daily For 7-21 Days, To Be Given Over 60 Minute

Content

  • Inf: Per 250 ml: Moxifloxacin 400mg (as Hcl).
  • Cap /Tab: Moxifloxacin 400mg

Pregnancy

Contraindicated

Stability

  • Fluoroquinolone Antibiotic

Contra Indications

  • Acute Myocardial Infarction, Bradycardia, Congenital Long Qtsyndrome, Electrolyte Disturbances, Heart Failure With Reduced Left Ventricular Ejection Fraction, History Of Symptomatic Arrhythmias, History Of Tendon Disorders Related To Quinolone Treatment, Liver Impairment

Precautions

  • Acute Myocardial Infarction, Bradycardia, Congenital Long Qtsyndrome, Electrolyte Disturbances, Heart Failure With Reduced Left Ventricular Ejection Fraction, History Of Symptomatic Arrhythmias, History Of Tendon Disorders Related To Quinolone Treatment, Liver Impairment

Lactation

  • Contraindicated

Side Effects

  • Angina
  • Arrhythmias
  • Constipation
  • Flatulence
  • Gastritis
  • Hyperlipidaemia
  • Palpitation
  • Sweating
  • Vasodilatation
  • Dyspnea
  • Abdominal Pain
  • Headache
  • Dizziness
  • Gi Disturbance
  • Qt Prolongation In Patients With Hypokalaemia
  • Abnormal Lfts
  • Pain And Phlebitis At Injection Site.
  • Rare: Amnesia
  • Dysphagia
  • Hyperglycaemia
  • Hypertension
  • Hyperuricaemia
  • In Coordination
  • Myopathy
  • Oedema
  • Peripheral Neuropathy
  • Stomatitis
  • Syncope
  • Vasculitis
  • Stevens-johnson Syndrome
  • Toxic Epidermalnecrolysis

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