Ofloxacin

Therapeutic Group

Quinolone Anti-bacterials

Indication Dosage

Urinary-tract Infections: 

Oral: 

  • Adult: 200-400 Mg Daily In The Morning; Increased If Necessary To 400 Mg Twice Daily, In Upper Urinary Tract Infections 

Complicated Urinary-tract Infection: 

By IV Infusion: 

  • Adult: 200 Mg Daily, Increased If Necessary To 400 Mg Twice Daily For Severe Or Complicated Infections, To Be Given Over At Least 30 Minutes For Each200mg 

Acute Or Chronic Prostatitis: 

Oral: 

  • Adult: 200 Mg Twice Daily For 28 Days 

Lower Respiratory-tract Infections: 

Oral: 

  • Adult: 400 Mg Daily In The Morning, Then Increased If Necessary To 400 Mg Twice Daily 

By IV Infusion: 

  • Adult: 200 Mg Twice Daily, Increased To 400 Mg Twice Daily, For Severe Or Complicated Infections, To Be Given Over At Least 30 Minutes For Each 200mg 

Skin And Soft-tissue Infections: 

Oral: 

  • Adult: 400 Mg Twice Daily 

By IV Infusion: 

  • Adult: 400 Mg Twice Daily, To Be Given Over At Least 30 Minutes For Each 200mg 

Uncomplicated Gonorrhea: 

Oral: 

  • Adult: 400 Mg As A Single Dose 

Uncomplicated Genital Chlamydial Infection, Nongonococcal Urethritis: 

Oral: 

  • Adult: 400 Mg Daily For 7 Days, As a single daily Dose Or In Divided Doses 

Pelvic Inflammatory Disease: 

Oral: 

  • Adult: 400 Mg Twice Daily For 14 Days 

Septicaemia: 

By IV Infusion: 

  • Adult: 200 Mg Twice Daily, Increased If Necessary To 400 Mg Twice Daily, For Severe Or Complicated Infections, To Be Given Over At Least 30 Minutes For Each 200mg 

Uncomplicated Cystitis: 

Oral:

  • Adult: 200 Mg Every 12 Hr For 3 Days (e. Coli Or K. pneumoniae) Or For 7 Days (other Pathogens), Prostatitis (e. Coli): 300 Mg Every 12 Hr For 6 Weeks. 
  • Children: Not Recommended.

Content

  • Iv Infusion 200mg: Per 100 ml: Ofloxacin Hci 220mg Equiv To 200mg Ofloxacin.
  • Cap /Tab 100mg /200mg /400mg: Ofloxacin 100mg /200mg /400mg.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Fluoroquinolone Antibiotic

Contra Indications

  • Epilepsy Or Lowered Seizure Threshold, History Of Tendinitis, Adolescents,

Precautions

  • Epilepsy Or Lowered Seizure Threshold, History Of Tendinitis, Adolescents,

Lactation

  • Contraindicated or Not Recommended.

Side Effects

  • Cough
  • Eye Irritation
  • Nasopharyngitis
  • Diarrhoea
  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Abdominal Pain
  • Anorexia
  • Anxiety
  • Arthralgia
  • Asthenia
  • Blood Disorders
  • Confusion
  • Depression
  • Disturbances In Vision
  • Dyspepsia
  • Eosinophilia
  • Hallucinations
  • Leucopenia
  • Myalgia
  • Rash
  • Sleep Disturbances
  • Thrombocytopenia
  • Tremor.
  • Rare: Antibiotic-associated Colitis
  • Convulsions
  • Dyspnea
  • Hepatic Dysfunction
  • Hepatitis
  • Hypotension
  • Interstitial Nephritis
  • Jaundice
  • Photosensitivity
  • Psychoses
  • Renal Failure
  • Symptoms Of Peripheral Neuropathy
  • Tendon Damage And Inflammation
  • Vasculitis

Available Brands