Pasireotide

Therapeutic Group

Pituitary And Hypothalamic Hormones And Analogues

Indication Dosage

Cushing's Disease When Surgery Has Failed Or Is Inappropriate: 

By Sc Inj: 

  • Adult: Initially 600 Mcg Twice Daily For 2 Months, Then Increased If Necessary To 900 Mcg Twice Daily, Consider Discontinuation If No Response Within 2 Months; Consult Product Literature

Content

  • Inj 0.3 /0.6 /0.9mg: Per 1 ml Amp: Pasireotide 0.3 /0.6 /0.9mg Per 1 ml; Solution

Pregnancy

Avoid

Stability

  • Somatostatin Analogue

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Avoid

Side Effects

  • Abdominal Pain
  • Alopecia
  • Anorexia
  • Anaemia
  • Bloating
  • Diarrhea
  • Flatulence
  • Gallstones
  • Gi Disturbances
  • Hyperglycaemia
  • Hypoglycaemia
  • Impaired Postprandial Glucose Tolerance
  • Nausea
  • Steatorrhoea
  • Vomiting
  • Adrenal Insufficiency
  • Arthralgia
  • Bradycardia
  • Decreased Appetite
  • Fatigue
  • Hypotension
  • Myalgia
  • Pruritus
  • Qt-interval Prolongation.
  • Rare: Pancreatitis

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