Proglumetacin
Therapeutic Group
Anti-inflammatory And Anti-rheumatic ProductsIndication Dosage
Painful Joint And Rheumatic Disorders: Arthritis, Poly-arthritis, Acute Articular Rheumatism, Osteoarthrosis Spondylarthritis Acute Gouty Arthritis, Muscular Sprains And Strains in Distortions And Fractures, Extra Articular And Peri-articular Affections:
- Adults: Initial: 450-600 Mg Daily In 2 Divided Doses At Meals For 2 Week. Maintenance: 300-450 Mg Daily In 2 Divided Doses At Meals.
- Children: Not Recommended.
Content
- Cap /Tab: Proglumetacin 150mg /300mg.
Pregnancy
Positive Evidence Of Risk: Use Only When No Safer Alternative Exists For A Serious Problem.
Stability
- Lndoleacetic Acid
Contra Indications
- Active Gi Bleeding Or Ulceration, History Of Gi Bleeding Or Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage Or Ulceration (two Or More Distinct Episodes), Severe Heart Failure, Aspirin/anti-inflammatory Induced Allergy, Hepatic And Renal Failure
Precautions
- Active Gi Bleeding Or Ulceration, History Of Gi Bleeding Or Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage Or Ulceration (two Or More Distinct Episodes), Severe Heart Failure, Aspirin/anti-inflammatory Induced Allergy, Hepatic And Renal Failure
Lactation
- Caution Advised, Avoid
Side Effects
- Abdominal Pain
- Angioedema
- Blood Disorders
- Bronchospasm
- Colitis
- Crohn's Disease
- Depression
- Diarrhoea
- Dizziness
- Drowsiness
- Fluid Retention
- Gi Bleeding And Ulceration
- Gi Disturbances
- Haematuria
- Persistent Headache (discontinue If Occur)
- Corneal Deposits
- Retinal Disturbances (perform Periodic Eye Tests On Long Term Use)
- Hearing Disturbances
- Hypersensitivity Reactions
- Nausea
- Nervousness
- Photosensitivity
- Raised Blood Pressure
- Rashes
- Renal Failure (especially In Patients With Preexisting Renal Impairment)
- tinnitus
- Vertigo.
- Rare: Hepatic Damage
- Interstitial Fibrosis Associated With Nsaids