Propofol

Therapeutic Group

Induction Of Anaesthesia:

By Slow IV Inj, Or By IV Infusion:

Adult 18-54 Years: Usual Dose 1.5-2.5 Mg/kg, To Bead Ministered At A Rate Of 20-40 Mg Every 10 Seconds Until Response; For Maintenance: Usual Dose 4-12 Mg/kg/hour, Alternatively (by Slow IV Injection) 25-50 Mg, Dose May Berepeated According To Response
Adult 55 Years And Over: Usual Dose 1-1.5 Mg/kg, To Be Administered At A Rate Of 20 Mg Every 10 Seconds Until Response; For Maintenance: Usual Dose 3-6 Mg/kg/hour, Alternatively (by slow IV Injection) 25-50 Mg, Dose May Berepeated According To Response

Sedation Of Ventilated Patients In Intensive Care:

By Continuous IV Infusion:

Induction Of Sedation For Surgical And Diagnostic Procedures:

By Slow IV Inj:

Adult: Initially 0.5-1 Mg/kg, To Be Administered Over 1-5 Minutes, Dose And Rate Of Administration Adjusted according To Desired Level Of Sedation And Response.

For Maintenance:

By Iiv Infusion:

Adult: Initially 1.5-4.5 Mg/kg/hour, Dose And Rate Ofadministration Adjusted According To Desired Level Ofsedation And Response, Followed By (by Slow IV Injection) 10-20 Mg, (if Rapid Increase In sedation Required), Patients Over 55 Years Or Debilitatedmay Require Lower Initial Dose And Rate Ofadministration

Inj /Inf 1%: Per ml: Propofol 10mg (1%); White, Aqueous, Isotonic Emulsions; Vehicle; Glycerol, Purified Egg Phosphatides, Sodium Hydroxide, Soyabean Oil & Water.

May Depress Neonatal Respiration If Used During Delivery.

Severe Cardiovascular And Respiratory Disease, Seizures, Hyperlipidaemia, Not Recommended For Children

Severe Cardiovascular And Respiratory Disease, Seizures, Hyperlipidaemia, Not Recommended For Children