Secukinumab

Therapeutic Group

Immunosuppressants

Indication Dosage

Psoriatic Arthritis, Ankylosing Spondylitis: 

By Sc Inj: 

  • Adult: 150 Mg Every Week For 5 Doses, Then Maintenance 150 Mg Every Month, Review Treatment If No Response Within 16 Weeks 

Psoriatic Arthritis With Concomitant Moderate To Severe Plaque Psoriasis Or If Inadequate Response To Anti-tonfa Treatment, Plaque Psoriasis: 

By Sc Inj: 

  • Adult: 300 Mg Every Week For 5 Doses, Then Maintenance 300 Mg Every Month, Review Treatment If No Response Within 16 Weeks

Content

  • Inj 150mg: Secukinumab150mg, Lyophilized Powder In A Single-use Vial For Reconstitution

Pregnancy

Avoid In Pregnancy

Stability

  • Immunosuppressants
  • Recombinant Human Monoclonal Interleukin-17a (il-17a) Antagonist

Contra Indications

  • Severe Active Infection, Serious Hypersensitivity Reaction.

Precautions

  • Severe Active Infection, Serious Hypersensitivity Reaction.

Lactation

  • Avoid During Treatment and for up to 20 Weeks After Discontinuing Treatment

Side Effects

  • Upper Respiratory Tract Infections
  • Diarrhoea
  • Oral Herpes
  • Rhinorrhoea
  • Conjunctivitis . Neutropenia (mild And Reversible)
  • Oral Candidiasis
  • Otitis Externa
  • Tinea Pedis
  • Exacerbations Of Inflammatory Bowel Disease.
  • Rare: Anaphylactic Reactions Or Other Serious Allergic Reaction And Cases Of Urticaria

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