Selegiline

Therapeutic Group

Anti-Parkinson Drugs

Indication Dosage

Selegiline is a medication that is used to help people with Parkinson's disease. It can improve their ability to move and reduce tremors, stiffness, and shakiness. It works by increasing the levels of certain chemicals in the brain that are important for controlling movement. Selegiline is often used in combination with other Parkinson's medications to provide better symptom control.

Parkinson's Disease, Used Alone Or As Adjunct To Cobeneldopaor Co-Careldopa To Reduce 'End Of Dose' Deterioration, Symptomatic Parkinsonism: 

  • Adult: Initially 5 Mg Once Daily For 2-4 Weeks, Then Increased If Tolerated To 10 Mg Daily, Dose To Be Taken In The Morning

Content

  • Tab: Selegiline 5mg.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk.

Stability

  • Mao-b Inhibitor

Contra Indications

  • Active Gastric Or Duodenal Ulceration, Avoid Or Use With Great Caution In Postural Hypotension (when Used In Combination With Levodopa)

Precautions

  • Active Gastric Or Duodenal Ulceration, Avoid Or Use With Great Caution In Postural Hypotension (when Used In Combination With Levodopa)

Lactation

  • Contraindicated, Avoid

Side Effects

  • Arthralgia
  • Agitation
  • Anxiety
  • Angina
  • Bradycardia
  • Confusion
  • Constipation
  • Depression
  • Diarrhoea
  • Dizziness
  • Dry Mouth
  • Fatigue
  • Hair Loss
  • Headache
  • Hypertension
  • Hypotension
  • Impaired Balance
  • Mouth Ulcers
  • Movement Disorders
  • Muscle Cramps
  • Myalgia
  • Myopathy
  • Nasal Congestion
  • Nausea
  • Psychosis
  • Sleeping Disorders
  • Stomatitis
  • Sweating
  • Tremor.
  • Rare: Arrhythmias
  • Blurred Vision
  • Dyspnea
  • Leucocytopenia
  • Palpitation
  • Postural Hypotension
  • Skin Reactions

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