Terbutaline
Therapeutic Group
Drugs For Obstructive Airway Diseases, SystemicIndication Dosage
Asthma, Conditions Associated With Reversible airways Obstruction:
Oral:
- Adult: Initially 2.5 Mg Tab 3 Times A Day For 1-2 Weeks, Then increased To Up To 5 Mg 3 Times A Day
- Children 7-15 Yr: 2.5 Mg Tab 2 Or 3 Times Daily
- Children 3-7 Yr: 2.5-5 Ml Syrup 8 Hourly;
- Children 7-15 Yr: 5-10 Ml Syrup 8 Hourly
By Sc Inj, Or By Slow IV Inj:
- Adult: 250-500 Mcg Up To 4 Times A Day, Use In Severe Cases Where Oral Therapy Is Inappropriate Or Ineffective
By Cont. Iv Infusion:
- Adult: 90-300 Mcg/hour For 8-10 Hours, To Beadministered As A Solution Containing 3-5 Mcg/ml, High Doses Require Close monitoring, Use In Severe Cases Where Oral Therapy Is Inappropriate Or Ineffective
Acute Asthma:
Oral:
- Adults: 2.5 Mg-5 Mg Tab 2 Or 3 Times Daily Or 10-15 Ml Syrup 8 Hourly
- Children 7-15 Yr: 2.5 Mg Tab 2 Or 3 Times Daily
- Children 3-7 Yr: 2.5-5 Ml Syrup 8 Hourly;
- 7-15 Yr: 5-10 Ml Syrup 8 Hourly
By Sc Inj, Or By Slow IV Inj:
- Children 2-14 Yrs: 10 Mcg/kg Up To 4 Times A Day(max. Per Dose 300 Mcg);
- 15-17 Years: 250-500 Micrograms Up To 4 Times Aday, Use In Severe Cases Where Oral Therapy Is Inappropriate Or Ineffective
By Cont. Iv Infusion:
- Children: Loading Dose 2-4 Mcg/kg, Then1-10 Mcg/kg/hour, Dose To Be Adjusted According To Response And Heart Rate, Close Monitoring is Required For Doses Above 10 Mcg/kg/hour, Use In Severe Cases Where Oral Therapy Is Inappropriate Or Uneffective
Exacerbation Of Reversible Airways Obstruction (including Nocturnal Asthma), Prevention Of Exercise-induced bronchospasm:
Oral:
- Children 1 Month-6 Yrs: 75 Mcg/kg 3 Times A Day (max. Per Dose 2.5 Mg);
- 7-14 Years: 2.5 Mg 2-3 Times A Day;
- 15-17 Years: Initially 2.5 Mg 3 Times A Day, Then increased If Necessary To 5 Mg 3 Times A Day,
Uncomplicated Premature Labour:
By IV Infusion:
- Adult: Initially 5 Mcg/minute For 20 Minutes, Then Increased In Steps Of 2.5 Mcg/minute Every 20 Minutes Until Contractions Have Ceased (more Than 10 Mcg/minute Should Seldom Be Given; Should Not Be Exceeded20 Mcg/minute), Continue For 1 Hour, Then Reduced In Steps Of 2.5 Mcg/minute Every 20 Minutes To Lowestdose That Maintains Suppression (maximum Total Duration 48 Hours)
Content
- Inj: Per ml: Terbutaline Sulphate 0.5mg; Amp.
- Syp: Per ml: Terbutaline Sulphate 0.3mg.
- Tab: Terbutaline Sulphate 2.5mg.
Pregnancy
Caution Advised
Stability
- Beta 2-adrenoceptor Agonists
Contra Indications
- When Used For Uncomplicated Premature Labour: Abruptio-placenta, Antepartum Haemorrhage, Cord Compression, Eclampsia, History Of Cardiac Disease, Intra-uterine Infection Or Fetal Death, Placenta Praevia, Pulmonary Hypertension, Severe Pre-eclampsia, Risk Factors For Myocardial Ischaemia, Threatened Miscarriage
Precautions
- When Used For Uncomplicated Premature Labour: Abruptio-placenta, Antepartum Haemorrhage, Cord Compression, Eclampsia, History Of Cardiac Disease, Intra-uterine Infection Or Fetal Death, Placenta Praevia, Pulmonary Hypertension, Severe Pre-eclampsia, Risk Factors For Myocardial Ischaemia, Threatened Miscarriage
Lactation
- Caution Advised
Side Effects
- Muscle Tension
- Nausea
- Pulmonary Oedema (with Injection Use) Vomiting
- Tremor
- Peripheral Vasodilation
- Tension
- Headache
- Sleep And Behavioural Disturbances In Children.