Thiopental

Therapeutic Group

Anaesthetic

Indication Dosage

Induction Of Anaesthesia, Anaesthesia Of Short Duration: 

By Slow IV Inj: 

  • Adult: Initially 100-150 Mg, To Be Administered Over 10-15 Seconds Usually As A 2.5% (25 Mg/ml) Solution, Followed By 100-150 Mg After 0.5-1 Minute If Required, Debilitated Patients Or Adults Over 65 Years May Require A Lower Dose Or Increased Administration Time, Alternatively Initially Up To 4 Mg/kg (max. Per Dose 500 Mg) 
  • Children 1 Month-18 Yrs: Initially Up To 4 Mg/kg Then 1 Mg/kg Repeated As Necessary (max Total Dose 7 Mg/kg). 

Reduction Of Raised Intracranial Pressure If Ventilation Controlled: 

By Slow IV Inj: 

  • Adult: 1.5-3 Mg/kg, Repeated If Necessary 

Status Epilepticus When Other Measures Fail: 

By Slow IV Inj: 

  • Adult: 75-125 Mg For 1 Dose, To Be Administered As A 2.5% (25 Mg/ml) Solution 
  • Children 1 Month-18 Yrs: Initially Up To 4 Mg/kg By Slow IV Injection, Then Up To 8 Mg/kg/hr By Continuous IV infusion, Adjusted According To Response.

Content

  • Inj 500mg: Thiopentone Sodium 500mg; Powder In Vials.

Pregnancy

Caution; May Depress Neonatal Respiration When Used During Delivery

Stability

  • General Anaesthetic

Contra Indications

  • Acute Porphyria; Myotonic Dystrophy.

Precautions

  • Acute Porphyria; Myotonic Dystrophy.

Lactation

  • Caution Advised

Side Effects

  • Arrhythmias
  • Headache
  • Myocardial Depression
  • Hypotension
  • Laryngeal Spasm
  • Rash
  • Sneezing
  • Cough
  • Hypersensitivity Reactions