Trimethoprim

Therapeutic Group

Sulfonamides And Trimethoprim

Indication Dosage

Urinary tract Infections, Respiratory Tract Infections: 

  • Adult & Children Above 12 Yrs: 200 Mg Twice Daily; 
  • Children 4 - 5 Weeks: 4 Mg/kg Twice Daily (max. Per Dose200 Mg); 
  • 6 Weeks - 5 Months: 4 Mg/kg Twice Daily (max. Per Dose 200 Mg), Alternatively 25 Mg Twice Daily; 
  • 6 Months - 5 Years: 4 Mg/kg Twice Daily (max. Per Dose 200 Mg), Alternatively 50 Mg Twice Daily; 
  • 6 - 11 Years: 4 Mg/kg Twice Daily (max. Per Dose 200 Mg), Alternatively 100 Mg Twice Daily 

Prophylaxis Of Urinary tract Infection, Recurrent Infection, Significant urinary tract Anomalies, Or Significant Kidney Damage: 

  • Adult & Children Above 12 Yrs: 100 Mg Once Daily; Dose To Be Taken At Night 
  • Children 4 - 5 Weeks: 2 Mg/kg Once Daily (max. Per Dose100 Mg); 
  • 6 Weeks - 5 Months: 2 Mg/kg Once Daily (max. Perdose 100 Mg), Alternatively 12.5 Mg Once Daily; 
  • 6 Months - 5 Years: 2 Mg/kg Once Daily (max. Per Dose 100 Mg), Alternatively 25 Mg Once Daily; 
  • 6 - 11 Years: 2 Mg/kg Once Daily (max. Per Dose100 Mg), Alternatively 50 Mg Once Daily. All Doses To Be Taken At Night 

Treatment Of Pneumocystis Jirovecii (pneumocystis Carinii) Pneumonia: 

  • Adult & Children: 5 Mg/kg Every 6-8 Hours 

Acne Resistant To Other Antibacterials: 

  • Adult: 300 Mg Twice Daily 

Prostatitis: 

  • Adult: (consult Product Literature) 

Shigellosis, Invasive Salmonella Infection: 

  • Adult: (consult Product Literature)

Content

  • Tab 100mg /200mg /300mg: Trimethoprim 100mg /200mg /300mg.
  • Susp: Per 5 ml: Trimethoprim 50mg.

Pregnancy

Contraindicated

Stability

  • Folic Acid Inhibitor

Contra Indications

  • Severe Renal In Sufficiency, Blood Dyscrasias

Precautions

  • Severe Renal In Sufficiency, Blood Dyscrasias

Lactation

  • Contraindicated

Side Effects

  • Abdominal Discomfort
  • Gi Disturbance
  • Allergic Reactions
  • Anaphylaxis
  • Angioedema
  • Erythema Multiforme
  • Photosensitivity
  • Toxic Epidermal Necrolysis
  • Aseptic Meningitis
  • Depression Of Haematopoiesis
  • Hyperkalaemia
  • Nausea
  • Pruritus
  • Rashes
  • Uveitis (in Adults)
  • vomiting

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