Generic Name
EverolimusPacks Price
- Tab 10 mg(069520): 30: 382500.00: 450000.00
- Tab 5 mg(069519): 30: 267750.000: 315000.00
- Tab 2.5 mg: 30: 177.813.67: 209.192.55
Afinitor
Therapeutic Group
Anti-neoplasticsIndication Dosage
Everolimus is a medication that is used to treat certain types of cancer and non-cancerous conditions. It works by slowing down the growth of abnormal cells in the body. Your doctor may prescribe Everolimus to help control the growth of tumors or to prevent the rejection of a transplanted organ.
Treatment Of Advanced Renal Cell Carcinoma When Uncontrolled With Vascular endothelial Growth Factor-targeted Therapy, Treatment Of Unresectable Or Metastatic, Differentiated Neuroendocrine Tumours Of Pancreatic Origin, Treatment Of Hormone-receptor-positive, Human epidermal Growth Factor-2 (her-2) Negative Advancedbreast Cancer, In Combination With Exemestane, In Postmenopausal Women:
- Adult: 10 Mg Once Daily
Liver Transplantation:
- Adult: Initially 1 Mg Twice Daily, Started approximately 4 Weeks After Transplantation; Maintenance, Dose Adjusted According To Response And Whole Blood Everolimus Concentration; Dose Adjustments Every 4-5 Days
Renal Transplantation, Heart Transplantation:
- Adult: Initially 750 Mcg Twice Daily, Started Soon After Transplantation; Maintenance, Dose Adjusted According To Response And Whole Blood Everolimus Concentration; Dose Adjustments Every 4-5 Days
Content
- Tab 0.1mg /0.25mg /0.75mg /5mg /10mg: Everolimus 0.25mg /0.75mg /5mg /10mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Protein Kinase Inhibitor
Contra Indications
- Hypersensitivity To Everolimus, Sirolimusor To Any Of The Ingredients In The Preparation, Patients With Rare Hereditary Problems Of Lactase Deficiency Or Glucose-galactose Mal-absorption Should Not Take This Medicine, Severe Hepatic Impairment.
Precautions
- Hypersensitivity To Everolimus, Sirolimusor To Any Of The Ingredients In The Preparation, Patients With Rare Hereditary Problems Of Lactase Deficiency Or Glucose-galactose Mal-absorption Should Not Take This Medicine, Severe Hepatic Impairment.
Lactation
- Contraindicated. Discontinue Breast-feeding.
Side Effects
- Abdominal Pain
- Anorexia
- Arthralgia
- Asthenia
- Chest Pain
- Convulsions
- Dehydration
- Diarrhoea
- Dry Mouth
- Dysphagia
- Electrolyte Disturbance
- Epistaxis
- Eyelid Oedema
- Fatigue
- Hand-foot Syndrome
- Headache
- Hypercholesterolaemia
- Hyperglycaemia
- Hyperlipidaemia
- Hypertension
- Hypoglycaemia
- Increased Susceptibility To Aspergillosis
- Increased Susceptibility To Candidiasis
- Increased Susceptibility To Infections
- Increased Susceptibility Topneumonia
- Insomnia
- Interstitial Lung Disease
- Irritability
- Nail Disorders
- Peripheral Oedema
- Pneumonitis
- Renal Failure
- Skin Disorders
- Taste Disturbance
- Congestive Heart Failure
- Flushing
- Impaired Wound Healing
- Rhabdomyolysis
- Alopecia
- Bone-marrow Suppression
- Haemorrhage
- Hepatitis B Reactivation
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting
Available Brands
Author
Shahid Arif