Avastin
Generic Name
Bevacizumab
Packs Price
- Inj100 mg(043004): 4 ml: 24480.00: 28800.00
- Inj400 mg(043005) 16 ml: 97325.00: 114500.00
Company
Roche
Therapeutic Group
Anti-neoplastics
Indication Dosage
Bevacizumab is a medication used to treat certain types of cancer. It works by slowing down the growth of blood vessels that supply nutrients to tumors, helping to stop the cancer from spreading and growing. Bevacizumab is often used in combination with other cancer treatments to improve their effectiveness.
Treatment Of Metastatic Colorectal Cancer, First-line Treatment Of Metastatic Breast Cancer In Combination With Other Chemotherapy, Advanced Or Metastatic Renal Cell Carcinoma, First-line Treatment Of Unresectable Advanced, Metastatic Or Recurrent Non-small Cell Lung Cancer, First-Line Treatment Of Advanced (Figo Stages Iiib, Iiic, And Iv)epithelial Ovarian, Fallopian Tube, Or Primary Peritoneal cancer, Metastatic Colon/rectum Carcinoma:
By IV Infusion:
- Adults: 5 Mg/kg IV Infusion Over 90 Min Once Every 14 days until Disease Progression Is Detected. If 1st Infusion Is Well Tolerated, Administer 2nd Infusion Over 60 Min. If 2nd Infusion Is Well Tolerated, Administer Subsequent Doses Over 30 Min.
Content
- Inf 25mg: Per ml: Bevacizumab 25mg; In 4 ml(100mg), 16 ml(400mg).
Pregnancy
Contraindicated Or Not Recommended.
Stability
- Monoclonal Antibody Antineoplastic
Contra Indications
- Elective Surgery, Nephrotic
Syndrome, Tracheo-oesophageal Or Grade 4 Fistula, Hypersensitivity To Drug
Precautions
- Elective Surgery, Nephrotic
Syndrome, Tracheo-oesophageal Or Grade 4 Fistula, Hypersensitivity To Drug
Lactation
- Contraindicated. Discontinue Breast-feeding.
Side Effects
- Abdominal Pain
- Alopecia
- Anaemia
-
Anorexia
- Arterial Thromboembolism
- Asthenia
- Bone-marrow Suppression
- Chest Pain
- Congestive Heart Failure
- Gi Disturbance
- Dehydration
- Drowsiness
- Dysarthria
- Dyspnea
- Exfoliative Dermatitis
- Extravasation
- Eye Disorders
- Fistulas
- Flushing
- Gall Bladder Perforation Gi Perforation
- Haemorrhage
- Hand-foot Syndrome
- Headache
- Hypersensitivity Reactions
- Hypertension
- Hyperuricaemia
- Hypotension
- Hypoxia
- infection
- Intestinal Obstruction
- Lethargy
- Mucocutaneous Bleeding
- Necrotising Fasciitis (discontinue)
- Neutropenia
- Oral Mucositis
- Osteonecrosis Of The Jaw
- Peripheral Neuropathy
- Posterior Reversible Encephalopathy Syndrome
- Proteinuria
- Pulmonary Hypertension
- Pyrexia
- Rhinitis
- Rigors
- Skin Discoloration
- Supraventricular Tachycardia
- Syncope
- Taste Disturbances
- Thrombocytopenia
- Thromboembolism
- Tumourlysis Syndrome
- Nausea And Vomiting