Generic Name
Bosentan MonohydratePacks Price
- Tab 62.5 mg: 14's: Rs. 1550
- Tab 125 mg: 14's: Rs. 2658
Bosmon
Therapeutic Group
Cardiac TherapyIndication Dosage
Bosentan Monohydrate is a medication primarily prescribed to treat pulmonary arterial hypertension (PAH). PAH is a serious condition characterized by high blood pressure in the arteries of the lungs, which can lead to difficulty breathing and reduced exercise capacity.
Pulmonary Arterial Hypertension:
- Adult: Initially 62.5 Mg Twice Daily For 4 Weeks, Then Increased To 125 Mg Twice Daily (max. Per Dose 250 Mg); Maximum 500 Mg Per Day
- Children: Not Recommended.
Systemic Sclerosis With Ongoing Digital Ulcer Disease To Reduce Number Of New Digital Ulcers:
- Adult: Initially 62.5 Mg Twice Daily For 4 Weeks, Then Increased To 125 Mg Twice Daily
- Children: Not Recommended.
Content
- Tab: Bosentan 62.5mg (as Monohydrate).
Pregnancy
Contraindicated In Pregnancy.
Stability
- Endothelin Receptor Antagonist
Contra Indications
- Hepatic Impairment, Hepatic Aminotransferase Levels >3x Upper Limit, Acute Porphyrias, Not To Be Initiated If Systemic Systolic Blood Pressure Is Below 85mmhg
Precautions
- Hepatic Impairment, Hepatic Aminotransferase Levels >3x Upper Limit, Acute Porphyrias, Not To Be Initiated If Systemic Systolic Blood Pressure Is Below 85mmhg
Lactation
- Not Recommended.
Side Effects
- Anaemia
- Diarrhea
- Flushing
- Gastro-oesophageal Reflux
- Headache
- Hypotension
- Oedema
- Palpitation
- Syncope
- Leucopenia
- Neutropenia Thrombocytopenia
- Urinary Tract Infection
- Dyspnoea
- Gi Upset
- Erythema
- Dermatitis.
- Rare: Liver Cirrhosis
- Liver Failure
Available Brands
Author
Shahid Arif