Generic Name
Estradiol Valerate and Cyproterone Acetate.Packs Price
- Tab (018207): 21: 609.17: 716.67
Climen
Therapeutic Group
Progesterones with EstrogensIndication Dosage
Estradiol valerate + cyproterone acetate is a combination medication used in hormone replacement therapy (HRT) for transgender women or individuals assigned to males at birth who are undergoing feminizing hormone therapy.
Estradiol valerate is a form of estrogen that is used to replace the naturally occurring hormone in the body. It helps to feminize the body by promoting the development of breasts, reducing body hair growth, and redistributing body fat to a more feminine pattern.
Cyproterone acetate is an anti-androgen that works by blocking the effects of testosterone in the body. It helps to reduce the levels of testosterone, which is a male hormone, and prevent its effects on the body. This can lead to a reduction in body and facial hair, a decrease in muscle mass, and a decrease in libido.
The combination of estradiol valerate and cyproterone acetate is effective in suppressing testosterone production and promoting feminization in transgender women. However, it is important to note that the use of hormone therapy should always be supervised by a healthcare provider and the medication should be taken as directed to minimize the risk of side effects.
Dosage:
- Estradiol valerate: 2 mg to 4 mg taken orally once daily
- Cyproterone acetate: 12.5 mg to 25 mg taken orally once daily
Content
- Estradiol valerate tablets: 1mg, 2mg, 4mg
- Cyproterone acetate tablets: 12.5mg, 25mg
Pregnancy
Not recommended
Stability
- Progesterone with Estrogens
Contra Indications
- who have a history of blood clots or are at high risk for blood clots
- who have a history of liver disease or significant liver impairment
- who are allergic to any of the ingredients in the medication
- who are pregnant or breastfeeding
- who have a history of breast cancer or other estrogens- or progestin-sensitive cancer
- who have unexplained vaginal bleeding
Precautions
- who have a history of blood clots or are at high risk for blood clots
- who have a history of liver disease or significant liver impairment
- who are allergic to any of the ingredients in the medication
- who are pregnant or breastfeeding
- who have a history of breast cancer or other estrogens- or progestin-sensitive cancer
- who have unexplained vaginal bleeding
Lactation
- Not recommended
Side Effects
- Nausea and vomiting
- Breast tenderness or enlargement
- Changes in sex drive
- Mood changes or depression
- Headache
- Fatigue
- Weight changes
- Changes in blood pressure
- Skin irritation or rash
- Abdominal pain
- Irregular menstrual bleeding or spotting
Author
Shahid Arif