Therapeutic Group

Indication Dosage

Indication:

Cyclophosphamide is a medication used to treat certain types of cancer and autoimmune diseases. It works by slowing down or stopping the growth of abnormal cells in the body. Your doctor may prescribe it to help fight cancer or manage conditions like lupus and rheumatoid arthritis.

Dosage:

Rheumatoid Arthritis With Severe Systemic Manifestations: 

Oral: 

• Adult: 1-1.5 Mg/kg Daily 

Severe Systemic Rheumatoid Arthritis and other Connective Tissue Diseases (especially With Active Vasculitis): 

By IV Inj: 

• Adult: 0.5-1g Every 2 Weeks, Then Reduced To 0.5-1g, With Prophylactic Mesna, Every Month, Frequency Adjusted According To Clinical Response And Haematological Monitoring. 

In Combination With Other Agents For Treatment Of A Wide Range Of Malignancies, Including Leukaemias, Lymphomas, Multiple Myeloma, Mycosis Fungoides, Neuroblastoma, Ovary Adenocarcinoma, Retinoblastoma, Breast Carcinoma And Solid Tumours: 

By IV Inj: 

• Adults & Children: 40-50 Mg/kg In Divided Doses Over 2-5 Days, Or 10-15 Mg/kg For 7-10 Days, Or 3-5 Mg/kg. 

Oral: 

• Adults & Children: 1-5 Mg/kg/day.

Content

Pregnancy

Positive Evidence Of Risk: Avoid

Stability

Contra Indications

Precautions

Lactation

Side Effects