Generic Name
Dapagliflozin And MetforminPacks Price
- Tab 5/850 mg: Pack Size 14's: Rs. 265
- Tab 5/1000 mg: Pack Size 14's: Rs. 330
Daplyza-M
Therapeutic Group
Blood Glucose Lowering Drugs, Excluding InsulinIndication Dosage
Dapagliflozin and Metformin is a medication used to treat type 2 diabetes. It helps lower blood sugar levels in people with this condition by improving the way their bodies use insulin and reducing the amount of sugar absorbed from the food they eat. This medication is typically prescribed by doctors to help manage and control diabetes and prevent complications associated with high blood sugar.
Type 2 Diabetes Mellitus Not Controlled By Metformin Alone Or By Metformin In Combination With Insulin Or Other Antidiabetic Drugs
Dosage:
- Adult 18-74 Years: 1 Tablet Twice Daily, Based On Patient's Current Metformin Dose
- Adult 75 Yrs And Above: Initiation Not Recommended
Content
- Tab 5 /8500mg: Dapagliflozin 5mg And Metformin 850mg,
- Tab 5 /1000mg: Dapagliflozin 5mg And Metformin 1000mg
Pregnancy
Contraindicated
Stability
- Sodium Glucose Co-transporter 2 Inhibitors (sglt2)
- Biguanide
Contra Indications
- Diabetic Ketoacidosis, Elderly Over 80 Yrs Age, Moderate To Severe Renal Failure, Severe Hepatic Failure, Volume Depletion, Acute Metabolic Acidosis Or Pre-coma, Acute Conditions Predisposing To Renal Impairment, Cardiac Or Respiratory Failure, Recent Mi, Alcoholism And Elderly (above 75yrs).
Precautions
- Diabetic Ketoacidosis, Elderly Over 80 Yrs Age, Moderate To Severe Renal Failure, Severe Hepatic Failure, Volume Depletion, Acute Metabolic Acidosis Or Pre-coma, Acute Conditions Predisposing To Renal Impairment, Cardiac Or Respiratory Failure, Recent Mi, Alcoholism And Elderly (above 75yrs).
Lactation
- Contraindicated
Side Effects
- Genital Infection
- Hypoglycaemia (in Combination With Insulin Or Sulfonylurea)
- Polyuria
- Pruritus
- Urinary Tract Infection
- Dysuria
- Haematocrit
- Volume Depletion (rare). Reports Of Altered Lfts
- Hepatitis
- Gi Upset
- Taste Disturbance
- Skin Reactions
- Reduced B12 Absorptions
- Abnormal Liver Function Tests
- Rarely Lactic Acidosis
Available Brands
Author
Shahid Arif