Generic Name
DeferasiroxPacks Price
- Tab 250mg: Rs.
- Tab 500mg: Rs.
Defera
Therapeutic Group
All Other Therapeutic Products, Anti-dotesIndication Dosage
Transfusion-related Chronic Iron Overload In Patients With Beta Thalassaemia Major Who Receive Frequent Blood Transfusions, Or Patients With Other Anaemias:
- Adult: Initially 10-30 Mg/kg Once Daily, Dose Adjusted According To Serum-ferritin Concentration And Amount Of Transfused Blood (consult Product Literature), Then Adjusted In Steps Of 5-10 Mg/kg Every 3-6 Months, Maintenance Dose Adjusted According To Serum-ferritin Concentration; Maximum 30-40 Mg/kg Per Day
Chronic Iron Overload When Desferrioxamine Is Contraindicated Or Inadequate In Non-transfusion-dependent Thalassaemia Syndromes:
- Adult: Initially 10 Mg/kg Once Daily, Then Adjusted In Steps Of 5-10 Mg/kg Every 3-6 Months, Maintenance Dose Adjusted According To Serum-ferritin Concentration And Liver-iron Concentration (consult Product Literature); Maximum 20 Mg/kg Per Day
Content
- Tab DisPersible 100mg /125mg /250mg /400mg /500mg: Deferasirox 100mg /125mg /250mg /400mg /500mg
- Tab 90mg /180mg /360mg: Deferasirox 90mg /180mg /360mg
Pregnancy
Avoid Unless Essential
Stability
- Oral Iron Chelator
Contra Indications
- None Known
Precautions
- None Known
Lactation
- Avoid
Side Effects
- Abdominal Distension And Pain
- Headache
- Constipation
- Diarrhoea
- Dyspepsia
- Gi Haemorrhage And Ulceration
- Nausea
- Vomiting
- Proteinuria
- Pruritus
- Raised Serum Creatinine
- Raised Transaminases
- Rash
- Anxiety
- Cataract
- Cholelithiasis
- Disturbances Of Hearing And Vision
- Dizziness
- Fatigue
- Gastritis
- Glucosuria
- Hepatitis
- Laryngeal Pain
- Maculopathy
- Oedema
- Pyrexia
- Renal Tubulopathy
- Skin Pigmentation
- Sleep Disorder.
- Rare: Oesophagitis
- Optic Neuritis
Available Brands
Author
Shahid Arif