Deston
Generic Name
Ondansetron
Packs Price
- Inj 8 mg: 5 Amp: 531.25: 625.00
- Tab 8 mg: 10: 297.50: 350.00
- Syp 4 mg/5 ml: 50 ml: 212.50: 250.00
Company
Pharmasol
Therapeutic Group
Anti-Emetic & Anti-Nauseants
Indication Dosage
Ondansetron is a medication commonly used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking the action of serotonin, a natural substance that can trigger nausea and vomiting.
Moderately Emetogenic Chemotherapy Or Radiotherapy:
Oral:
- Adult: 8 Mg, 1-2 Hours Before Treatment, Then 8 Mg Every 12 Hrs For Up To 5 Days.
By Rectum:
- Adult: 16 Mg, 1-2 Hours Before Treatment, Then 16 Mg Daily For Up To 5 Days.
By IM Inj, Or By SlowIV Inj:
- Adult: 8 Mg, Immediately Before Treatment, Then (oral) 8 Mg Every 12 Hours For Up To 5 Days, Alternatively (by Rectum) 16 Mg Daily For Up To 5 Days.
By IM Inj, Or By IV Infusion:
- Elderly: 8 Mg, Immediately Before Treatment, IV infusion To Be Given Over At Least 15 Minutes, Then (oral) 8 Mg Every 12 Hours For Up To 5 Days, Alternatively (by Rectum) 16 Mg Daily For Up To 5 Days
Severely Emetogenic Chemotherapy:
Oral:
- Adult: 24 Mg, Dose To Be Taken 1-2 Hours Before Treatment, Then 8 Mg Every 12 Hours For Up To 5 Days
By Rectum:
- Adult: 16 Mg, Dose To Be Administered 1-2 Hours Before Treatment, Then 16 Mg Daily For Up To 5 Days
By IM Inj, Or By SlowIV Inj:
- Adult: 8 Mg, Dose To Be Administered Immediately Before Treatment, Followed By (by IM Inj Or By Slow IV Inj) 8 Mg Every 4 Hours If Required For 2 Doses, Alternatively, this is Followed By (by Continuous IV infusion) of 1 Mg/hour For Up To 24 Hours, Then (oral) 8 Mg Every 12 Hours For Up To 5 Days, and Alternatively (by Rectum) of 16 Mg Daily For Up To 5 Days.
- Children 6 Months-18 Yrs: By IV Infusion Over At Least 15 Minutes, 150 Mcg/kg Immediately Before Chemotherapy (max Single Dose 8 Mg) Repeated Every 4 hours for 2 Further Doses, Then Give By Mouth; Max Total Daily Dose 32mg. Oral Dosing Can Start 12 hours after IV administration; For Body weight 10 Kg Or Less, 2 Mg Every 12 Hr For Up To 5 Days (max Total Daily Dose 32 Mg); for Body weight Over 10 Kg, 4 Mg Every 12 Hr For Up To 5 Days (max Total Daily Dose 32 Mg); Bodyweight Over 40 Kg, 8 Mg Every 12 Hr For Up To 5 Days (max Total Daily Dose 32 Mg).
Prevention And Treatment Of Postoperative Nausea And Vomiting:
Oral:
- Adult: 16 Mg, Dose To Be Taken 1 Hour Before Anaesthesia,
By IM Inj Or By Slow IV Inj:
- Adult: 4 Mg, Dose To Be Administered At Induction Of Anaesthesia
- Children 1 Months-18 Yrs: 100 Mcg/kg (max 4 Mg) As A Single Dose By Slow IV Injection Over At Least 30 Sec, Before, During, Or After Induction Of An-aesthesia.
Content
- Inj 4mg /8mg: Per ml: Ondansetron 2mg; 4mg(2 ml) /8mg(4 ml); Solution In Amp.
- Tab 4mg /8mg: Ondansetron 4mg /8mg.
- Syp: Per 5 ml: Ondansetron 4mg.
Pregnancy
Caution Advised
Stability
Contra Indications
Precautions
Lactation
Side Effects
- Constipation
- Headache
- Flushing
- Arrhythmias
- Bradycardia
- Chest Pain
- Hiccups
- Hypotension
- Movement Disorders
- Seizure
- Transient Rise In Liver Enzymes
- St Segment Depression
- Extra-pyramidal Reactions
- Visual Disturbance.