Pain And Inflammation In Rheumatic Disease Including Juvenile Idiopathic Arthritis:
Oral:
Adult: 75-150 Mg Daily In 2-3 Divided Doses
Children 6 Months -18 Yrs: 1.5-2.5 Mg/kg (max 75 Mg) Twice Daily; Total Daily Dose May Alternatively Be Given In 3 Divided Doses
By Rectum:
Adult: 75-150 Mg Suppositories Daily In Divided Doses;
Children 6 Months-18 Yr: Body-weight 8-12 Kg: 12.5 Mg Suppositories Twice Daily For Max 4 Days; Body-weight Over 12 Kg: 1 Mg/kg Suppositories (max 50 Mg) 3 Times Daily For Max 4 Days.
By IV Infusion Or Deep IM Inj:
Children 2-18 Yr: 0.3-1 Mg/kg Once Or Twice Daily Iv Infusion Or Deep IM Injection Into Gluteal Muscle, For Max 2 Days (max 150 Mg Daily).
Pain And Inflammation In Musculoskeletal Disorders, Acute Goutrheumatoid Arthritis, Osteoarthrosis, Ankylosing Spondylitis, Acute Gout:
Oral:
Adult: 75-150 Mg Daily In 2-3 Divided Doses
By Rectum:
Adult: 75-150 Mg Suppositories Daily In Divided Doses
Children 2-18 Yrs: Body-weight 8-12 Kg: 12.5 Mg Suppositories Twice Daily For Max 4 Days; Body-weight Over 12 Kg: 1 Mg/kg Suppositories (max 50 Mg) 3 Times Daily For Max 4 Days.
By IM Inj:
Adult: 75 Mg Once Or Twice Daily By Deep Intragluteal Inj For Max 2 Days. Continue If Necessary With Tab.
Acute Postoperative Pain, Acute Back Pain, Pain In Acute Trauma And Fractures, Renal Colic:
Oral:
Adult: 75-150 Mg Daily In 2-3 Divided Doses
Children 6 Months -18 Yrs: 1.5-2.5 Mg/kg (max 75 Mg) Twice Daily; Total Daily Dose May Alternatively Be Given In 3 Divided Doses
By Rectum:
Adult: 75-150 Mg Suppositories Daily In Divided Doses;
Children 2-18 Yrs: Body-weight 8-12 Kg: 12.5 Mg Suppositories Twice Daily For Max 4 Days; Body-weight Over 12 Kg: 1 Mg/kg Suppositories (max 50 Mg) 3 Times Daily For Max 4 Days.
By IV Inj:
Adult: 75 Mg Repeated Every 4-6 Hr If Necessary, Max 150 Mg In 24 Hr. Prevention Of Postoperative Pain: A Loading Dose Of 25-50 Mg Should Be Infused After Surgery Over 15 Min To 1 Hour, Followed By Continuous Infusion Of About 5 Mg Per Hour Up To a Maximum of 150 Mg In 24 Hours.
Moderate To Severe Postoperative Pain, 75 Mg Infused Continuously Over A Period Of 30 Min To 2 Hours.
By IV Infusion Or Deep IM Inj:
Children 2-18 Yr: 0.3-1 Mg/kg Once Or Twice Daily Iv Infusion Or Deep IM Injection Into Gluteal Muscle, For Max 2 Days (max 150 Mg Daily).
By IM Inj:
Adult: 75 Mg Once Or Twice Daily By Deep Intragluteal Inj For Max 2 Days. Continue If Necessary With Tab.
Active Or Recurrent GI bleeding Or Ulceration, Cerebrovascular Disease, History Of GI bleeding Or GI perforation Related To Previous Nsaid Therapy, History Of Recurrent GI haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment, Aspirin/anti-inflammatory Induced Allergy.
With Intravenous Use: Dehydration, History Of Asthma, History Of Confirmed Or Suspected Cerebrovascular Bleeding,.
Precautions
Active Or Recurrent GI bleeding Or Ulceration, Cerebrovascular Disease, History Of GI bleeding Or GI perforation Related To Previous Nsaid Therapy, History Of Recurrent GI haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment, Aspirin/anti-inflammatory Induced Allergy.
With Intravenous Use: Dehydration, History Of Asthma, History Of Confirmed Or Suspected Cerebrovascular Bleeding,.
Lactation
Contraindicated or Not Recommended.
Side Effects
Angioedema
Blood Disorders
Bronchospasm
Colitis
Crohn's Disease
Depression
Diarrhoea
Dizziness
Drowsiness
Fluid Retention
Gi Bleeding And Ulceration
Gi Disturbances
Haematuria
Headache
Hearing Disturbances
Hypersensitivity Reactions
Insomnia
Nausea
Nervousness
Photosensitivity
Raised Blood Pressure
Rashes
Renal Failure (especially In Patients With Preexisting Renal Impairment)
