Do-One
Generic Name
Domperidone
Packs Price
- Susp 5 mg/5 ml: 120 ml: 81.60: 96.00
Company
Global
Therapeutic Group
Anti-Emetic & Anti-Nauseants
Indication Dosage
Domperidone is a medication used to treat certain digestive problems such as nausea, vomiting, bloating, and discomfort caused by delayed emptying of the stomach. It works by blocking dopamine receptors in the brain and gut, which increases the motility of the gastrointestinal tract and speeds up the movement of food through the stomach and intestines. Domperidone is usually prescribed for short-term use and should be taken under the guidance of a healthcare professional.
Relief Of Nausea And Vomiting:
By IV Inj:
- Adults: With Chemotherapy 1-40 Mg Iv (usually 1mg/ Kg). See Literature.
Oral:
- Adult & Children 12yrs (body weight 35 Kg And Above): 10 Mg Up To 3 Times A Day; Maximum 30 Mg Per Day.
- Children (body weight Up To 35 Kg): 250 Mcg/kg Up To 3 Times A Day; Maximum 750 Mcg/kg Per Day.
- Children Below 12yrs: Not Recommended.
Epigastria, Sense Of Fullness, Upper Abdominal Distention, Regurgitation, And Gastro-intestinal Pain In Palliative Care:
Oral:
- Adult: 10 Mg 3 Times A Day, Before Meals.
Content
- Inj 10mg: Per 2 ml Amp: DomPeridone 10mg.
- Susp /Syp 5mg: Per 5 ml: DomPeridone 5mg.
- Tab /Cap 10mg: DomPeridone 10mg.
Pregnancy
Contraindicated
Stability
- Dopamine Receptor Antagonists
Contra Indications
- Cardiac Disease, When Administered Concomitantly With Drugs That Prolong The Qt Interval Or Potent Cyp3a4 Inhibitors, Hepatic Impairment, Prolactinoma, Gi Haemorrhage, Mechanical Perforation Or Obstruction.
Precautions
- Cardiac Disease, When Administered Concomitantly With Drugs That Prolong The Qt Interval Or Potent Cyp3a4 Inhibitors, Hepatic Impairment, Prolactinoma, Gi Haemorrhage, Mechanical Perforation Or Obstruction.
Lactation
Side Effects
- Drowsiness
- Dry Mouth
- Malaise Anxiety
- Diarrhoea
- Galactorrhoea
- Headache
- Pruritus
- Rash
- Agitation
- Amenorrhoea
- Convulsions
- Extra Pyramidal Disorders
- Gynaecomastia
- Nervousness
- Oculogyric Crisis
- Qt-interval Prolongation
- Sudden Cardiac Death
- Urinary Retention
- Ventricular Arrhythmias
- Gi Upset
- Raised Serum Prolactin