Therapeutic Group

Indication Dosage

Vulvovaginal Candidiasis: 

• Adult: 200 Mg Twice Daily For 1 Day 

Prophylaxis For Recurrent: 

• Adult: 50-100 Mg Daily For 6 Months 

Oral Or Oesophageal Candidiasis That Has Not Responded To Fluconazole: 

• Adult: 100-200 Mg Twice Daily For 2 Weeks (continue For Another 2 Weeks If No Response; The Higher Dose Should Not Be Used For Longer Than 2 Weeks) 

Systemic Candidiasis Where Other Antifungal Drugs In Appropriate Or Ineffective: 

• Adult: 100-200 Mg Once Daily; Or 200 Mg Twice Daily In Invasive Or Disseminated Disease 

Pityriasis Versicolor: 

• Adult: 200 Mg Once Daily For 7 Days 

Tineapedis, Tineamanuum: 

• Adult: 100 Mg Once Daily For 30 Days, Alternatively 200 Mg Twice Daily For 7 Days 

Tineacorporis, Tineacruris: 

• Adult: 100 Mg Once Daily For 15 Days, Alternatively 200 Mg Once Daily For 7 Days 

Onychomycosis: 

• Adult: 200 Mg Once Daily For 3 Months, Alternatively 200 Mg Twice Daily For 7 Days, Subsequent Courses Repeated After 21-day Intervals; Fingernails 2 Courses, Toe Nails 3 Courses 

Aspergillosis: 

• Adult: 200 Mg Twice Daily 

Histoplasmosis: 

• Adult: 200 Mg 3 Times A Day For 3 Days, Then 200 Mg 1-2 Times A Day 

Systemic Cryptococcosis Including Cryptococcal Meningitis Where Other Antifungal Drugs Inappropriate Or Ineffective: 

• Adult: 200 Mg Once Daily, Dose Increased In Invasive Or Disseminated Disease And In Cryptococcal Meningitis, Increased To 200 Mg Twice Daily 

To Prevent Relapse Of Underlying Fungal Infection In Hiv-infected Patients And Prophylaxis In Neutropenia When Standard Therapy Inappropriate: 

• Adult: 200 Mg Once Daily, Then Increased To 200 Mg Twice Daily, Dose Increased Only If Low Plasma-itraconazole Concentration 

Prophylaxis Of Deep Fungal Infections In Patients With Haematological Malignancy Or Undergoing Bone-marrow Transplantation (when Standard Therapy Inappropriate): 

• Adult: 5 Mg/kg Daily In 2 Divided Doses, To Be Started Before Transplantation Or Before Chemotherapy (taking Care To Avoid Interaction With Cytotoxic Drugs) And Continued Until Neutrophil Count Recovers, Safety And Efficacy Not Established In Elderly Patients

Content

Pregnancy

Caution Advised

Stability

Contra Indications

Precautions

Lactation

Side Effects