Therapeutic Group

Indication Dosage

Irinotecan HCl is indicated for the treatment of certain types of cancer. It is commonly used in the management of metastatic colorectal cancer when other treatments have not been effective. Additionally, Irinotecan HCl may be prescribed for the treatment of small-cell lung cancer when used in combination with other chemotherapy agents.

Metastatic Colorectal Cancer In Combination With Fluorouracil And Folinic Acid Or As Monotherapy When Treatment Containing Fluorouracil Has Failed, Treatment of Epidermal Growth Factor Receptor-expressing Metastatic Colorectal Cancer After Failure Of chemotherapy That Has Included Irinotecan (in combination With Cetuximab), First-line Treatment Of metastatic Carcinoma Of The Colon Or Rectum (in combination With Fluorouracil, Folinic Acid Andbevacizumab Or Capecitabinewith Or Without Bevacizumab): 

By IV Infusion: 

• Adult: 350 Mg/m2 Over 30-90 Min Every 3 Week. If the Patient Develops Severe Neutropenia Or Severe Diarrhoea Reduce the Dose To 300 Mg/m, And Then 250 Mg/m, In Subsequent Cycles. Consult Product Literature. Continue Treatment Until Disease Progression Or Unacceptable Toxicity. 
• Children: Not Recommended.

Content

Pregnancy

Positive Evidence Of Risk: Avoid

Stability

Contra Indications

Precautions

Lactation

Side Effects