Legent
Generic Name
Topiramate
Packs Price
- Tab 25 mg (052511): 6x10: 765.00: 900.00
- Tab 50 mg (052512): 6x10: 1020.00: 1200.00
Company
Amarant
Therapeutic Group
Anti-epileptics
Indication Dosage
Topiramate is a medication that is used to help with different health conditions:
- Seizures: It's used to prevent and control seizures in people with epilepsy.
- Migraines: It can reduce the frequency and severity of migraine headaches.
- Weight Loss: Sometimes, doctors prescribe it to help people lose weight when other methods haven't worked.
- Bipolar Disorder: In some cases, it may be used to stabilize mood in people with bipolar disorder.
Dosage:
Monotherapy Of Generalised Tonic-clonic Seizures Or Focal Seizures With Or Without Secondary Generalization:
- Adult: Initially 25 Mg Once Daily At Night, For 1 Week, Then Increased In Steps Of 25-50 Mg Every 1-2 Weeks; Usual Dose 100-200 Mg Daily In 2 Divided Doses, Adjusted According To Response, Maximum 500 Mg Per Day; Doses Of 1 G Daily Have Been Used In Refractory Epilepsy
- Children 6-17 Yrs: Initially 0.5-1 Mg/kg Once Daily At Night, (max. Per Dose 25 Mg) For 1 Week, Then Increased In Steps Of 250-500 Mcg/kg Twice Daily, At Intervals Of 1-2 Weeks; Usual Dose 50 Mg Twice Daily (max. Per Dose 7.5 Mg/kg Twice Daily), If Child Cannot Tolerate Titration Then Smaller Steps Or Longer Interval Between Steps May Be Used; Maximum 500 Mg Per Day
Adjunctive Treatment Of Generalised Tonic-clonic Seizures Or Focal Seizures With Or Without Secondary Generalization, Adjunctive Treatment For Seizures Associated With Lennox-gastaut Syndrome:
- Adult: Initially 25-50 Mg Once Daily At Night, For 1 Week, Then Increased In Steps Of 25-50 Mg Every 1-2 Weeks; Usual Dose 200-400 Mg Daily In 2 Divided Doses; Maximum 400 Mg Per Day
- Children 2-17 Yrs: Initially 1-3 Mg/kg Once Daily At Night, (max. Per Dose 25 Mg) For 1 Week, Then Increased In Steps Of 0.5-1.5 Mg/kg Twice Daily, Dose To Be Increased By A Maximum Of 25 Mg Twice Daily At Intervals Of 1-2 Weeks; Usual Dose 2.5-4.5 Mg/kg Twice Daily (max. Per Dose 7.5 Mg/kg Twice Daily), If Child Cannot Tolerate Then Smaller Steps Or Longer Interval Between Steps May Be Used; Maximum 400 Mg Per Day
Migraine Prophylaxis:
- Adult: Initially 25 Mg Once Daily At Night, For 1 Week, Then Increased In Steps Of 25 Mg Every Week; Usual Dose 50-100 Mg Daily In 2 Divided Doses; Maximum 200 Mg Per Day
Content
- Tab 25mg /50mg /100mg /200mg: Topiramate 25mg /50mg /100mg /200mg.
- Cap 15mg /25mg /50mg: Topiramate 15mg /25mg /50mg.
Pregnancy
Avoid Unless The Potential Benefit Outweighs The Risk.
Stability
Contra Indications
Precautions
Lactation
Side Effects
- Abdominal Pain
- Aggression
- Agitation
- Alopecia
- Anaemia
- Anxiety
- Appetite Changes
- Arthralgia
- Cognitive Impairment
- Confusion
- Constipation
- Depression
- Diarrhoea
- Dizziness
- Drowsiness
- Dry Mouth
- Dyspepsia
- Dyspnea
- Epistaxis
- Gastritis
- Impaired Attention And Coordination
- Irritability
- Malaise
- Movement Disorders
- Muscle Spasm
- Muscular Weakness
- Myalgia
- Nausea
- Nephrolithiasis
- Nystagmus
- Paraesthesia
- Pruritus
- Rash
- Seizures
- Sleep Disturbance
- Speech Disorder
- Taste Disturbance
- Tinnitus
- Tremor
- Urinary Disorders
- Visual Disturbances
- Vomiting