Generic Name
Zoledronic AcidPacks Price
- Inf 5 mg/100ml: 1: 20,575.10: 24,206.18
- Inj IV 4 mg/5ml: 19779.19:23.226.64
Macdronic
Therapeutic Group
Drugs For Treatment Of Bone DiseasesIndication Dosage
Treatment Of Paget's Disease Of Bone:
By IV Infusion:
- Adult: 5 Mg As A Single Dose, To Be Administered Over At Least 15 Minutes, 500mg Elemental Calcium Twice Daily (with Vitamin D) For a Minimum 10 Days Is Recommended Following Infusion
Treatment Of Postmenopausal Osteoporosis And Osteoporosis In Men (including Corticosteroid-induced Osteoporosis):
By IV Infusion:
- Adult: 5 Mg Once Yearly As A Single Dose, To Be Administered Over At Least 15 Minutes, In Patients With A Recent Low-trauma Hip Fracture, The Dose Should Be Given 2 Or More Weeks Following Hip Fracture Repair; Before First Infusion Give 50000-125000 Units Of Vitamin D
Reduction Of Bone Damage In Advanced Malignancies Involving Bone:
By IV Infusion:
- Adult: 4 Mg Every 3-4 Weeks, To Be Administered Over At Least 15 Minutes, Calcium 500mg Daily And Vitamin D 400 Units Daily Should Also Be Taken
Hypercalcemia Of Malignancy:
By IV Infusion:
- Adult: 4 Mg For 1 Dose, To Be Administered Over At Least 15 Minutes
- Children: Not Recommended.
Content
- Inj 4mg: Per ml: Zoledronic Acid 800 Mcg; 5 ml (4mg) Concentrate For Iv Infusion.
- Inj 5mg: Per ml, Zoledronic Acid 50 Mcg; 100 ml Bottle, For Iv Infusion.
Pregnancy
Contraindicated
Stability
- Bisphosphonate
Contra Indications
- Acute Gastro-intestinal Inflammatory Conditions, Hypersensitivity To Other Bisphosphonate.
Precautions
- Acute Gastro-intestinal Inflammatory Conditions, Hypersensitivity To Other Bisphosphonate.
Lactation
- Contraindicated
Side Effects
- Bronchospasm
- Diarrhoea
- Nausea
- Hypophosphataemia
- Hypocalcaemia
- Creatinine/urea Increase
- Anaemia
- Headache
- Conjunctivitis
- Anorexia
- Fatigue
- Skin Reactions
- Vomiting
- Renal Impairment
- Uveitis.
- Rare: Atypical Femoral Fractures
- Steonecrosis Of The External Auditory Canal
- Osteonecrosis Of The Jaw
Available Brands
Author
Shahid Arif