Artemether is a medication primarily indicated for the treatment of malaria, a potentially life-threatening mosquito-borne disease caused by Plasmodium parasites. It is specifically effective against Plasmodium falciparum, the most deadly malaria parasite species. Artemether works by rapidly reducing the number of parasites in the bloodstream, thereby alleviating symptoms and aiding in the recovery from malaria infection. This medication is an essential tool in the global fight against malaria and is often used in combination with other antimalarial drugs to enhance its efficacy and reduce the risk of resistance development.
Severe Malaria Including Cerebral Malaria And As A Second Line Treatment In Chloroquine-resistant Falciparum Malaria:
By IM Inj Or Iv Infusion:
Adults: First Dose 120 Mg; Followed By 60 Mg After 4-6 Hr; Then 60 Mg After Every 24 Hr Once Daily. The Total Duration Of Treatment Is 5 Consecutive Days. Total Doses Are 360-480Mg For Adults.
Children Below 7 Yr Age: 1.5 Mg/kg; 7 Yrs Or Above, Same As Adult Dose. Both The Age Group Children Should Be Given The Second Dose After 4-6 Hr; Then One Dose After Every 24 Hr Once Daily. The Total Duration Of Treatment Is 5 Consecutive Days.
Content
Inj 40mg /80mg: Artemether 40mg /80mg; Amp.
Inj Paeds 20mg: Artemether 20mg; Amp.
Cap 40mg: Artemether 40mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
Artemisinin Derivative
Contra Indications
Family History Of Congenital Qt Interval Prolongation Family History Of Sudden Death. History Of Arrhythmias. History Of Clinically Relevant Bradycardia .history Of Congestive Heart Failure Accompanied By Reduced Left Ventricular Ejection Fraction Electrolyte Disturbances, Concomitant Use With Other Drugs Known To Cause Qt-interval Prolongation.
Precautions
Family History Of Congenital Qt Interval Prolongation Family History Of Sudden Death. History Of Arrhythmias. History Of Clinically Relevant Bradycardia .history Of Congestive Heart Failure Accompanied By Reduced Left Ventricular Ejection Fraction Electrolyte Disturbances, Concomitant Use With Other Drugs Known To Cause Qt-interval Prolongation.
Lactation
Caution Advised or Effect Undetermined.
Side Effects
Transient And Reversible Reticulocytopenia
Drug Fever
Drug Rash
Bradycardia
Transient First Degree Heart Block And Transient & Reversible Elevation Of Serum Transaminases
